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Fig. 1. Sequence comparison of Hes proteins across species. (A) The amino acid sequences of human (Hs), mouse (Mm), zebrafish (Dr), Xenopus tropicalis (Xt), Xenopus laevis (Xl) Hes3 genes were aligned using ClustalX2. Hes3 amino acid conservation among species is highlighted in different shades of grey. The b-HLH is underlined in blue and the Groucho-binding domain is underlined in red. (B) Phylogenetic tree of Hes proteins from Xenopus laevis (Xl), human (Hs) mouse (Mm), chicken (Gg) and zebrafish (Dr).

Image published in: Hong CS and Saint-Jeannet JP (2018)

Copyright © 2018. Image reproduced with permission of the Publisher, Elsevier B. V.

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