Figure 1. Effects of SR-A competitive and non-competitive ligands on the cell-associated FV3 loads in four tadpole cell lines. The American toad BufoTad cell line, bullfrog BullTad-leg cell line, green frog GreenTad-HF2 cell line, and wood frog WoodTad-rpe cell line were pre-treated with 250 g/mL of the SR-A competitive ligands (fucoidan, poly inosine (pI)) (A–D) or non-competitive ligands (fetuin, poly cytosine (pC)) (E–H) for 30 min. FV3 was added at an multiplicity of infection MOI of 1.0 for 2 h. The FV3 DNA viral loads were determined by absolute qPCR. Data are presented as means SEM (n = 3). Statistical analysis using a one-way ANOVA test and Tukey’s multiple comparisons test with 95% confidence intervals was performed. p values less than 0.05 are considered statistically significant. Groups with different letters are statistically different from one another.
Image published in: Vo NTK et al. (2019)
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