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Fig. 1. Expression pattern of Xprx1 during hindlimb development. (A) Lateral view of a stage 45 tadpole. Transcripts were restricted to the prospective limb-forming region (arrow). (B) A longitudinal section of a limb bud at stage 50. Note that mesenchymal expression is restricted to the limb bud. An arrow indicates the boundary between the limb bud and trunk mesodermal tissues. (C) A longitudinal section of a limb bud blastema at stage 53 shows expression of Xprx1 similar to that in the limb bud. Dotted lines indicate the amputation plane. (D) A longitudinal section of a thigh region at stage 56. Transcripts were preferentially detected in the perichondrium and undifferentiated mesenchyme. (E and F) Serial sections of panel D stained with Alcian blue (cartilage) and myosin heavy chain (muscle), respectively. Scale bars: 200 μm. ab, abdomen; ca, presumptive cartilage-forming region; mf, medial fin fold; ms, muscle; tr, trunk.

Image published in: Suzuki M et al. (2007)

Copyright © 2007. Image reproduced with permission of the Publisher, Elsevier B. V.

GeneSynonymsSpeciesStage(s)Tissue
prrx1.LLOC108714489, LOC108715742, phox1, pmx1, prx-1, prx1, xprx-1X. laevisThroughout NF stage 45mesenchyme
limb bud
hindlimb bud
prrx1.LLOC108714489, LOC108715742, phox1, pmx1, prx-1, prx1, xprx-1X. laevisThroughout NF stage 50limb bud
mesenchyme
hindlimb bud
prrx1.LLOC108714489, LOC108715742, phox1, pmx1, prx-1, prx1, xprx-1X. laevisSometime during NF stage 53 to NF stage 54mesenchyme
regenerating hindlimb
prrx1.LLOC108714489, LOC108715742, phox1, pmx1, prx-1, prx1, xprx-1X. laevisThroughout NF stage 56connective tissue
mesenchyme
hindlimb
perichondrium
myh1.LE19X. laevisThroughout NF stage 56muscle
limb bud

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