Fig. 1. The spatial expression pattern of X. laevis PPan. (A-C) PPan is expressed in the neural plate (arrows), as monitored from stage 12 to 18. (D) At stage 23, PPan transcripts accumulate in the eye (red arrow), the cranial neural crest cells (NCCs; white arrow), and in the posterior part of the embryo (left). (E) Arrows point to the different PPan expression domains at stage 28: eye (red), forebrain (green), midbrain (violet), branchial arches (white) and pronephros (yellow). (F,G) PPan is expressed in the hypaxial muscles (F, arrow) and the blood islands (G, arrow) at stage 36. (H) Transverse section (plane indicated in F) of the eye at stage 36 shows PPan expression in the ciliary marginal zone (CMZ; arrows) and in the lens. (I) Transverse section (plane indicated in F) at stage 36 indicates PPan expression in the branchial arches (arrows). (J) Transverse section of the eye shows PPan protein localized in the CMZ (arrows) and in the lens.
Image published in: Bugner V et al. (2011)
Copyright © 2011. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| ppan.L | bxdc3, Peter Pan, ppan-a, ppan-b, ssf, ssf1, ssf2 | X. laevis | Throughout NF stage 12 | neural plate neuroectoderm |
| ppan.L | bxdc3, Peter Pan, ppan-a, ppan-b, ssf, ssf1, ssf2 | X. laevis | Throughout NF stage 15 | neural plate neuroectoderm |
| ppan.L | bxdc3, Peter Pan, ppan-a, ppan-b, ssf, ssf1, ssf2 | X. laevis | Throughout NF stage 18 | anterior neural fold neuroectoderm neural plate neural crest |
| ppan.L | bxdc3, Peter Pan, ppan-a, ppan-b, ssf, ssf1, ssf2 | X. laevis | Throughout NF stage 23 | neural crest cranial neural crest migratory neural crest cell eye primordium tail region mesoderm neuroectoderm anterior neural tube |
| ppan.L | bxdc3, Peter Pan, ppan-a, ppan-b, ssf, ssf1, ssf2 | X. laevis | Throughout NF stage 28 | forebrain midbrain eye pronephric kidney cranial neural crest brain midbrain-hindbrain boundary tail bud paraxial mesoderm pronephric mesenchyme pharyngeal arch mandibular arch hyoid arch branchial arch otic vesicle |
| ppan.L | bxdc3, Peter Pan, ppan-a, ppan-b, ssf, ssf1, ssf2 | X. laevis | Throughout NF stage 35 and 36 | lens forebrain midbrain ciliary marginal zone eye pronephric kidney brain midbrain-hindbrain boundary otic vesicle pharyngeal arch mandibular arch hyoid arch branchial arch paraxial mesoderm tail bud ventral blood island hypaxial muscle somite |
| ppan.L | bxdc3, Peter Pan, ppan-a, ppan-b, ssf, ssf1, ssf2 | X. laevis | Throughout NF stage 42 | lens ciliary marginal zone |
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