Fig. 4. Induction of xFog expression by growth factors. (A) Semiquantitative RT-PCR analysis at stage 24, of xFog expression after growth factor induction in animal cap assays. Key: −, no reverse transcriptase; Ac, Activin; B, BMP-4; Sm, Xmad; Vg, AVg; F+, bFGF; F−, without growth factor; W, whole embryo. BMP- 4, Smad and Avg each induce xFog, whereas xGata-1 is induced by BMP-4 and Smad, only. ODC is the RNA loading control. (B) In whole embryos, BMP-4 signaling increases the area of xFog expression (top panel; ventralized embryos) compared to uninjected sibling controls (bottom panel).
Image published in: Deconinck AE et al. (2000)
Copyright © 2000. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| bmp4.L | bmp-4, bmp2b, bmp2b1, bmp4-a, bmp4-b, DVR-4, ofc11, XBMP-4, xbmp4, zyme | X. laevis | Throughout NF stage 24 | heart ventral blood island otic vesicle |
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