Figure 3 Overexpression of Nxfz3 suppresses expression of genes regulating eye development. A whole-mount in situ hybridization analysis was made of stage 180 embryos that are either uninjected (a, c, and e) or Nxfz3 injected (b, d, and f) and then labeled for Xpax6 (a and b), Xrx (c and d), or Xotx2 expression (e and f). β-Galactosidase (sky blue) marks the regions of the embryo derived from the injected blastomere.
Image published in: Rasmussen JT et al. (2001)
Copyright © 2001. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| pax6.L | an2, mgda, pax-6, pax6-a, pax6-b, wagr, XLPAX6, xpax6 | X. laevis | Sometime during NF stage 18 to NF stage 20 | eye primordium neural plate preplacodal ectoderm anterior placodal area posterior placodal area optic field |
| rax.S | rax-a, rax-b, rax1, rx, rx-1, rx1, rx1a, Rx2A, Xrax, Xrx1, Xrx1A | X. laevis | Sometime during NF stage 18 to NF stage 20 | eye eye primordium |
| otx2.S | otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 | X. laevis | Sometime during NF stage 18 to NF stage 20 | anterior neural tube anterior placodal area forebrain |
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