Figure 4. pSmad1 Dynamics in the Xenopus Foregut(A) Diagram of a stage 20 Xenopus embryo section showing the foregut (fg) region in green that was isolated for western blots and imaged by confocal.(B) Immunoblot of pSmad1/5/8, total Smad1 and tubulin levels in foregut explants at the indicated developmental stages, with the pSmad1/total Smad1 ratio quantitated above.(C) Immunostaining of pSmad1/5/8 (red) and nuclei (green) in the foregut of bisected embryos at the indicated stage shows spatially and temporally dynamic BMP signaling in the foregut. White dashed lines indicate the boundaries between the endoderm (end), mesoderm (m), and ectoderm (ect).
Image published in: Kenny AP et al. (2012)
Copyright © 2012. Image reproduced with permission of the Publisher, Elsevier B. V.
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