Figure 6. Expression of connexin genes in frog and chick embryos. A: Cx31 is expressed in the posterior margin of the area pellucida in the chick embryo at stage (st.) 4+ (arrows). B: Cx47 is expressed within the posterior third of the primitive streak at st. 4 (arrow). Cx37 is expressed in the early primitive streak (arrow, C), and in a punctate pattern identifying a subset of the cells of the primitive ridges and neural plate at st. 7 (arrows, D). In Xenopus, maternal Cx40 mRNA is in the anterior pole of the two-cell embryo (arrow, E) and then in a band perpendicular to the animalegetal axis in the four-cell embryo (arrow, F). G: During blastula stages, it is expressed in the cells of the animal cap (arrowhead). H: Radioactive in situ hybridization on sections shows that Cx38 is present in the animal cap and in gastrulating cells (arrow, radioactive section). Cx41 mRNA is spread throughout the animal pole of the two-cell embryo (arrow, I) but is only detected in the nucleus by the four-cell stage (arrow, J). Red arrows indicate domain of expression.
Image published in: Rutenberg J et al. (2002)
Copyright © 2002. Image reproduced with permission of the Publisher, John Wiley & Sons.
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