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Fig. 2. (A) Whole-mount in situ hybridization with labeled antisense probes against XMEF2D, XMEF2A and XMEF2C during embryonic development. The numbers refer to the developmental stages. The anterior side of the embryos is on the left. Lateral view for all embryos except dorsal view for XMEF2D stages 12, 16 and 20; XMEF2A stages 16 and 20; and anterior view for XMEF2C stage 19. (B) XMEF2A, XMEF2D and XMEF2C expression at stages 37–38 in head muscle anlagens as indicated by XMRF4 mRNAs localization. Lateral view on the left. ba, brachial arches; cm, cranio-facial muscle; fhr, frontal head region; nc, neural crest; h, heart; hm, hypaxial muscles. Arrowhead: hypaxial migratory cells.

Image published in: della Gaspera B et al. (2009)

Copyright © 2009. Image reproduced with permission of the Publisher, Elsevier B. V.

GeneSynonymsSpeciesStage(s)Tissue
mef2d.SXMEF2D, sl1, sl-1, mef2d-b, mef2d-aX.laevisThroughout NF stage 12presomitic mesoderm
mef2c.LXMEF2CX.laevisSometime during NF stage 19 to NF stage 22cranial neural crest
mef2a.Lxmef2a, adcad1, rsrfc4, rsrfc9, sl2, sl-2X.laevisSometime during NF stage 16 to NF stage 20presomitic mesoderm
neural plate
myf6.Lmrf4, Xmrf4, herculin, myf6-a, myf6-b, XMRF4a, XMRF4-aX.laevisThroughout NF stage 37 and 38head region
muscle
mef2d.SXMEF2D, sl1, sl-1, mef2d-b, mef2d-aX.laevisSometime during NF stage 16 to NF stage 20neural plate
mesoderm
mef2d.SXMEF2D, sl1, sl-1, mef2d-b, mef2d-aX.laevisThroughout NF stage 25mesoderm
somite
fused heart primordium
mef2d.SXMEF2D, sl1, sl-1, mef2d-b, mef2d-aX.laevisThroughout NF stage 29 and 30head
head region
muscle
myotome
somite
branchial arch
mef2d.SXMEF2D, sl1, sl-1, mef2d-b, mef2d-aX.laevisThroughout NF stage 32head region
muscle
somite
hatching gland
fused heart primordium
tail somite
optic vesicle
mef2d.SXMEF2D, sl1, sl-1, mef2d-b, mef2d-aX.laevisThroughout NF stage 37 and 38 to NF stage 40head region
muscle
somite
hypaxial muscle
tail region
mef2c.LXMEF2CX.laevisThroughout NF stage 28cranial neural crest
mandibular crest
branchial crest
hyoid crest
fused heart primordium
mef2c.LXMEF2CX.laevisThroughout NF stage 29 and 30muscle
somite
branchial arch
mef2c.LXMEF2CX.laevisThroughout NF stage 33 and 34head region
muscle
myotome
somite
trunk somite
mef2c.LXMEF2CX.laevisThroughout NF stage 35 and 36head region
muscle
myotome
somite
hypaxial muscle
fused heart primordium
mef2c.LXMEF2CX.laevisSometime during NF stage 37 and 38 to NF stage 40head region
muscle
somite
hypaxial muscle
mef2a.Lxmef2a, adcad1, rsrfc4, rsrfc9, sl2, sl-2X.laevisSometime during NF stage 23 to NF stage 29 and 30somite
trunk somite
mesoderm
muscle
myotome
mef2a.Lxmef2a, adcad1, rsrfc4, rsrfc9, sl2, sl-2X.laevisThroughout NF stage 32head region
muscle
myotome
somite
trunk somite
mef2a.Lxmef2a, adcad1, rsrfc4, rsrfc9, sl2, sl-2X.laevisSometime during NF stage 37 and 38 to NF stage 40head region
muscle
myotome
somite
hypaxial muscle
head mesoderm

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