Cell & Developmental Biology of Xenopus: Gene Discovery & Disease 2019 Course at Cold Spring Harbor

March 25 - April 7, 2020

This course is designed for those new to the Xenopus field, as well as for more advanced students who are interested in emerging technologies.

Application & Materials Deadline: January 31, 2020

Xenopus stem cells used to build living programmable organisms

Kriegman et al. published in PNAS their study producing biological machines using Xenopus embryonic tissue.

Trachea-esophageal Disease Studies Using Xenopus

Back to back papers published in Developmental Cell from Nasr et al. and Kim et al. recapitulate human congenital trachea-esophageal birth defects using Xenopus.

Xenopus tropicalis v10 genome

- available to BLAST

- view on JBrowse

99.86% of the genome mapped to chromosomes
~4500 new and refined models, 18% not present in trop v9.1

Click here to view the release document.

Xenbase v4.12.1 Release

Included in the latest Xenbase release:

- Xenopus tropicalis genome v10 sequence and assembly

- GEO GSE visualization (view our tutorial video) 

Xenbase Tutorials: GEO Data Simple and Advanced Search

Please view the Xenbase tutorial videos for the simple and advanced search interface for Xenopus GEO datasets.

Added tutorial: Navigating a GSE page.

The Allied Genetics Conference 2020

Gaylord National Resort & Convention Center
Metro Washington, DC
April 22–26, 2020

Abstract deadline, Dec. 13, 2019

Early Registration deadline, Dec.20, 2019

The invited Xenopus speaker is John Wallingford (UT Austin, USA).

TAGC2020 website

The Epigenetic Control of Pluripotent Signal Competence

Gentsch et al. demonstrate that maternal pluripotency factors initiate epigeneic remodelling of thousands of regulatory elements on which signal mediators act to regionalise zygotic genome activity, specifying the three germ layers. Their discovery is a first step in understanding how proteins permit a cell type-specific signal response. Published in Nature Communications.

Defining the vertebrate cardiac proteome

Federspiel et al. published in PLoS Biology their study identifying the core protein composition, complexes, and pathways in vertebrates from Xenopus to human heart. They reveal that each species shares a unique set of proteins with humans but not the other vertebrates studied.

Cell & Developmental Biology of Xenopus: Gene Discovery & Disease 2019 Course at Cold Spring Harbor

March 25 - April 7, 2020

This course is designed for those new to the Xenopus field, as well as for more advanced students who are interested in emerging technologies.

Application & Materials Deadline: January 31, 2020