2020 Xenopus White Paper

The 2020 Xenopus Community White Paper is now available!

PIs: Please reference the White Paper in your NIH grant proposals and contact your program officers.

Download the 2020 Xenopus White Paper:

Word Document

PDF

Professor Anna Philpott elected member of EMBO

Dr. Anna Philpott of the University of Cambridge elected to membership of the European Molecular Biology Organization (EMBO) for 2020.

GBrowse on Xenbase

Archived genomes viewable on GBrowse.

As well as...

X. laevis v9.2

X. tropicalis v9.1 and v10.0

Coming soon.

Click "read more" on how to access archived genomes on Xenbase GBrowse:

Long-term transcription factor binding stabilizes gene expression

Gurdon et al., published in PNAS, show that long-term (hours to days as opposed to seconds) non-competitive binding of transcription factors such as neurogenic Ascl1 stabilizes gene expression.

Autism risk gene dyrk1a is required for ciliogenesis and brain size

Willsey & Xu et al., using X. tropicalis, show that mutations in the neurodevelopmental disorder risk gene, dyrk1a, disrupts cell cycle progression and ciliogenesis causing brain defects. Published in Development.

ATAC-seq in Xenopus

Esmaeili et al. published in Developmental Biology their ATAC-seq study assessing chromatin accessibility during Xenopus gastrulation.

Processed ATAC-seq data viewable on JBrowse coming soon.

18th International Xenopus Conference

The meeting has been postponed to August 15-19, 2021.

Portsmouth, UK at the EXRC

Uncovering selective cooperation between the retinoblastoma and p53 cancer pathways in X. tropicalis

Naert, Dimitrakopoulou et al. (2020) published in Oncogene their study describing the first frog model for the Li-Fraumeni Syndrome to study leukemia and malignant sarcoma.

Xenopus tropicalis v10 genome

- available to BLAST

- view on JBrowse

99.86% of the genome mapped to chromosomes
~4500 new and refined models, 18% not present in trop v9.1

Click here to view the release document.

2020 Xenopus White Paper

The 2020 Xenopus Community White Paper is now available!

PIs: Please reference the White Paper in your NIH grant proposals and contact your program officers.

Download the 2020 Xenopus White Paper:

Word Document

PDF