Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
  • Xenbase v4.4

    Xenbase launched 4 new features (June 2017, Xenbase v 4.4).

    1. NEW Interactive RNA-seq temporal expression graphs for trop and laevis.

    2. View the latest ‘Xenopus Research Articles

    3. NEW Interactive gene-interaction visualization.

    4. Xenopus Article Page, now includes a list of references cited in the paper.

    Read More...
  • 8th International Course on Developmental Biology

    This course is to provides participants with comprehensive coverage of paradigms, problems and technologies of modern Developmental Biology with a particular attention to stem cells.

    Workshop: September 18-October 7, 2017/ Seminars: October 9-20, 2017.

    Paris, France

     

    Read More...
  • miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA

    Bellon et al. published in Cell Reports the role of microRNAs in mRNA-specific translation during axonal pathfinding of Xenopus laevis retinal ganglion cells (RGCs). They found that miR-182 targets cofilin-1 mRNA, silencing its translation. Slit2 rapidly relieves this repression without causing miR-182 degradation. Their data support a model where miR-182 reversibly gates the selection of certain mRNAs for fast translation depending on extrinsic cues.

    we investigate the local role of miRNAs in mRNA-specific translation during pathfinding of Xenopus laevis retinal ganglion cell (RGC) axons.
    Read More...
  • Leftward Flow Determines Laterality in Conjoined Twins

    Tisler et al. published in Current Biology their study of an enigmatic left-right defect in conjoined twins. Twins fused at the thorax: left twins are normal, laterality is disturbed in one-half of right twins due to insufficient suppression of the Nodal inhibitor, dand5.

    Read More...
  • Gene Regulatory Networks White Paper 2016

    A “final” draft of the GRN white paper is in the works, but several people request that the current working white paper draft be made publicly available.

    This would allow everyone to refer to the white paper in grants or manuscripts. The GRN White Paper draft will be hosted on Xenbase.

    This current draft will eventually be replaced with the final 2016 version.

    Click here to download the draft of the GRN White Paper.

    Read More...
  • GO: Gene Ontology terms on Xenbase

    Expanded representation of Gene Ontology (GO) terms associated with gene product function added to Xenopus gene pages.

    Look for the tab on gene summary pages...

    Read More...
  • Genesis Special Issue - Xenopus: Advances and Emerging Technologies

    Check out the January 2017 issue of Genesis highlighting current advances using Xenopus as a biomedical research model.

    Read More...
  • Genome evolution in the allotetraploid frog Xenopus laevis

    Session et al. published in Nature describe the analysis of the subgenomes of the allotetraploid Xenopus laevis. The L subgenome more consistenly resembles the ancestral condition and the S subgenome is more disrupted by deletion and rearrangment.

    Read More...
  • Updated Xenopus laevis genome annotation

    Gene Model Annotation 1.8.3 of the X. laevis 9.1 Genome Build

    The latest annotation of the X. laevis 9.1 genome is ready!  

    This release only includes updating the gene symbol of existing gene models.  

    The files for this annotation release, GFFs and FASTA, can be downloaded from the Xenbase FTP page, under the X. laevis genome assemblies and gene models category.

    Read More...
  • 2016 Xenopus White Paper

    Representatives of the research community have released the 2016 Xenopus White Paper summarizing strategic resource development.

    Download: Word Doc, PDF

    PIs: Please reference the White Paper in your NIH grant proposals and contact your program officers.

    Read More...
  • Xenbase v4.4

    Xenbase launched 4 new features (June 2017, Xenbase v 4.4).

    1. NEW Interactive RNA-seq temporal expression graphs for trop and laevis.

    2. View the latest ‘Xenopus Research Articles

    3. NEW Interactive gene-interaction visualization.

    4. Xenopus Article Page, now includes a list of references cited in the paper.

    Read More...
BLASTBLAST Xenopus

BLAST X. tropicalis and X. laevis nucleotide and protein sequences, ESTs clusters, and genomes:

Sequences
X. laevis genomes
X. tropicalis genomes
BLAST archives

genome_browserGenome Browsers

Browse the genomes using the Xenbase genome browsers:

X. laevis genomes X. tropicalis genomes

UCSC Track Hubs:

Other Genome Browsers:
Browser archives
gene_expressionGene Expression

Search our gene expression patterns by anatomy and developmental stage:


Search NCBI gene expression datasets:

genesGenes

Search gene catalogs and gene expression images:


View Nomenclature Guidelines:


Perform data mining with Xenopus data:

anatomy_and_developmentAnatomy & Development

View anatomy and developmental stage information and resources:

reagents_and_protocolsReagents & Protocols

Browse Xenopus reagents, ABs, MOs, protocols, and suppliers:

literatureLiterature

Search for research papers and books about Xenopus:


Run advanced queries on Xenopus papers with Textpresso:


Papers on Xenbase:

My Xenbase: [ Log-in / Register ]
version: [4.4.0]

Please consider citing us in your papers if Xenbase contributes to your research

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556