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  • Xenbase Tutorials: GEO Data Simple and Advanced Search

    Please view the Xenbase tutorial videos for the simple and advanced search interface for Xenopus GEO datasets.

    Added tutorial: Navigating a GSE page.

    Read More...
  • Xenbase v4.11 Release

    Xenopus expression data from GEO available. Viewable on JBrowse.

    View our tutorial video.

    X. laevis protein expression profiles on gene pages.

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  • Basal cells in Xenopus mucociliary epithelium

    Haas et al. using Xenopus mucociliary epidermis, the mouse airway, and human airway basal cells demonstrate that wnt is necessary for cilia formation during differentiaion. In basal cells, wnt prevents specification of epithelial cell types by activating the master transcription factor, ΔN-Tp63 which is required to retain basal cell stemness during development. Published in Cell Reports.

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  • The Epigenetic Control of Pluripotent Signal Competence

    Gentsch et al. demonstrate that maternal pluripotency factors initiate epigeneic remodelling of thousands of regulatory elements on which signal mediators act to regionalise zygotic genome activity, specifying the three germ layers. Their discovery is a first step in understanding how proteins permit a cell type-specific signal response. Published in Nature Communications.

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  • Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome

    Greenberg et al. published in Cell their study of the developmental disorder, Floating-Harbor syndrome (FHS) caused by mutations in the chromatin remodelling gene, SRCAP which functions through H2A.Z.2-containing nucleosomes, regulating AT-rich enhancers.

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  • Roberto Mayor elected new member by EMBO

    Dr. Roberto Mayor, Professor of Developmental and Cellular Neurobiology at University College London’s Division of Biosciences, was elected by The European Molecular Biology Organization (EMBO) as a new member.

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  • Defining the vertebrate cardiac proteome

    Federspiel et al. published in PLoS Biology their study identifying the core protein composition, complexes, and pathways in vertebrates from Xenopus to human heart. They reveal that each species shares a unique set of proteins with humans but not the other vertebrates studied.

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  • 10th Course Developmental Biology Institut Curie

    September 16 - October 16, 2019 - practicals and lectures
    October 7-17, 2019 - lectures

    Registration deadline: July 15, 2019

    website

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  • The Allied Genetics Conference 2020

    Gaylord National Resort & Convention Center
    Metro Washington, DC
    April 22–26, 2020

    The Xenopus Keynote Speaker will be John Wallingford (UT Austin, USA).

    TAGC2020 website

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  • Xenopus Resources and Emerging Technologies Meeting 2019

    October 11-14, 2019 at the National Xenopus Resource Center, MBL, Woods Hole, MA, USA.

    Registration now open: click here.

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  • Genome Editing Workshop 2019

    October 14-24, 2019

    National Xenopus Research Center, MBL at Woods Hole, MA, USA.

    Read More...
  • Xenbase Tutorials: GEO Data Simple and Advanced Search

    Please view the Xenbase tutorial videos for the simple and advanced search interface for Xenopus GEO datasets.

    Added tutorial: Navigating a GSE page.

    Read More...
BLASTBLAST Xenopus

BLAST X. tropicalis and X. laevis nucleotide and protein sequences, ESTs clusters, and genomes:

Sequences
X. laevis genomes
X. tropicalis genomes
BLAST other amphibians

BLAST archives

gene_expressionGene Expression

Search gene expression patterns by anatomy and developmental stage:


Proteomics:


Search gene expression datasets:

anatomy_and_developmentAnatomy & Development

View anatomy and developmental stage information and resources:


Search Disease Ontology (DO) and OMIM:

reagents_and_protocolsReagents & Protocols

Browse Xenopus reagents, ABs, MOs, protocols, and suppliers:

literatureLiterature

Search for research papers and books about Xenopus:


Advanced search with Textpresso:


Papers on Xenbase:

communityCommunity

Browse community meetings, resources, information, and people:

Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.0


Major funding for Xenbase is provided by grant P41 HD064556