Xenbase Image ID: 173832

Figure 1 – Ten of the genes identified as exhibiting rax-dependent expression are expressed in the developing eye. A – J: Xenopus laevis embryos were fixed and subjected to in situ hybridization using antisense riboprobes specific for 10 of the genes identified as exhibiting rax-dependent expression in the microarray screen described in the text. Genes/riboprobes are identified to the left of each row. Embryos used were late neurula (st 18 – 20, column 1), with the exception of J1 (st 22), early tailbud (st 24 and 25, column 2), mid tailbud (st 25 – 31, column 3), and mid-late tailbud (st 30 – 33, column 4). Lateral views are shown for all embryos except for A1, B1, C1, D1, G1, H1, I1, where anterior views are shown. In all cases, dorsal is towards the top of the figure. Abbreviations and marks: arrowhead – eye; * - brain; B – branchial arches; P – pronephros. Image published in: Pan Y et al. (2018) Copyright © 2018. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue XB5768883.L LOC100498624, LOC108715400, MGC86492 X. laevis Throughout NF stage 18 fam50a.S fam50a-a, fam50a-b, hxc-26, xap5 X. laevis Throughout NF stage 18 optic vesicle eye primordium neural plate pre-chordal neural plate chordal neural plate cranial neural crest bnip3.L X. laevis Throughout NF stage 18 optic vesicle eye primordium optic field neural plate pre-chordal neural plate chordal neural plate sox11.L sox11-a, sox11-b, XLS13, xls13a, XLS13b, xSOX-11, xsox11 X. laevis Throughout NF stage 18 eye primordium optic field neural plate pre-chordal neural plate cbx5.L HP1-a, HP1a, HP1-alpha, HP1alpha X. laevis Sometime during NF stage 18 to NF stage 24 optic vesicle abcf2.L abc28, hussy-18, hussy18, LOC101731820, m-abc1 X. laevis Throughout NF stage 20 eye primordium optic field neural plate cox4i1.L cox4, coxiv, MGC85216 X. laevis Throughout NF stage 20 eye primordium optic field neil3.L X. laevis Sometime during NF stage 20 to NF stage 24 optic vesicle eye eye primordium fam50a.L fam50a-a, fam50a-b, hxc-26, xap5 X. laevis Throughout NF stage 22 eye primordium optic field XB5768883.L LOC100498624, LOC108715400, MGC86492 X. laevis Throughout NF stage 24 trigeminal nerve neural tube fam50a.L fam50a-a, fam50a-b, hxc-26, xap5 X. laevis Throughout NF stage 24 optic vesicle eye abcf2.L abc28, hussy-18, hussy18, LOC101731820, m-abc1 X. laevis Sometime during NF stage 24 to NF stage 25 optic vesicle eye cox4i1.L cox4, coxiv, MGC85216 X. laevis Throughout NF stage 25 optic vesicle eye fam50a.S fam50a-a, fam50a-b, hxc-26, xap5 X. laevis Throughout NF stage 25 optic vesicle eye cranial neural crest neural tube bnip3.L X. laevis Throughout NF stage 25 optic vesicle eye neural tube posterior neural tube e2f7.L X. laevis Throughout NF stage 26 optic vesicle eye primordium cbx5.L HP1-a, HP1a, HP1-alpha, HP1alpha X. laevis Throughout NF stage 26 eye olfactory bulb neil3.L X. laevis Throughout NF stage 26 optic vesicle eye fam50a.L fam50a-a, fam50a-b, hxc-26, xap5 X. laevis Throughout NF stage 26 eye trunk sox11.L sox11-a, sox11-b, XLS13, xls13a, XLS13b, xSOX-11, xsox11 X. laevis Sometime during NF stage 26 to NF stage 28 optic vesicle eye eye primordium brain forebrain midbrain hindbrain abcf2.L abc28, hussy-18, hussy18, LOC101731820, m-abc1 X. laevis Throughout NF stage 28 eye pharyngeal arch cox4i1.L cox4, coxiv, MGC85216 X. laevis Throughout NF stage 28 optic vesicle eye central nervous system spinal cord brain hindbrain pronephric mesenchyme fam50a.S fam50a-a, fam50a-b, hxc-26, xap5 X. laevis Sometime during NF stage 28 to NF stage 32 optic vesicle eye central nervous system spinal cord brain forebrain midbrain hindbrain pharyngeal arch abcf2.L abc28, hussy-18, hussy18, LOC101731820, m-abc1 X. laevis Throughout NF stage 29 and 30 eye central nervous system pharyngeal arch XB5768883.L LOC100498624, LOC108715400, MGC86492 X. laevis Throughout NF stage 29 and 30 eye neil3.L X. laevis Throughout NF stage 29 and 30 eye e2f7.L X. laevis Throughout NF stage 31 eye brain forebrain midbrain hindbrain otic vesicle cbx5.L HP1-a, HP1a, HP1-alpha, HP1alpha X. laevis Throughout NF stage 32 eye olfactory bulb cox4i1.L cox4, coxiv, MGC85216 X. laevis Throughout NF stage 32 eye central nervous system spinal cord brain forebrain midbrain hindbrain pronephric kidney pronephric nephron pronephric tubule proximal tubule sox11.L sox11-a, sox11-b, XLS13, xls13a, XLS13b, xSOX-11, xsox11 X. laevis Throughout NF stage 32 eye brain forebrain midbrain hindbrain pharyngeal arch XB5768883.L LOC100498624, LOC108715400, MGC86492 X. laevis Throughout NF stage 33 and 34 eye central nervous system spinal cord brain forebrain midbrain hindbrain e2f7.L X. laevis Throughout NF stage 33 and 34 eye brain forebrain midbrain hindbrain bnip3.L X. laevis Throughout NF stage 33 and 34 eye brain forebrain midbrain hindbrain fam50a.L fam50a-a, fam50a-b, hxc-26, xap5 X. laevis Throughout NF stage 33 and 34 eye brain forebrain midbrain hindbrain pharyngeal arch trunk Image source: Published Larger Image Printer Friendly View

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