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Fig. 2. SSCs express tph1. (A) Expression pattern of tph1 mRNA at stage 31. Signals were detected in the brain and in a punctate pattern in the epidermis. A sagittal histological section (A′) demonstrated tph1expression in the epiphysis (A′) in SSCs and in a subset of neuronal cells (n) in the floor plate of the neural tube (A′′). (B) SSCs express tph1 (blue arrowhead), as demonstrated by whole-mount in situ hybridization followed by IF for serotonin (green, green arrowhead) and cilia (acetylated-α-tubulin, red, red arrowhead). (C) Punctate expression pattern of aromatic-L-amino-acid decarboxylase (DOPA-decarboxylase; ddc) in the embryonic skin. Inset shows close-up. Embryos are shown in lateral views. a, anterior; d, dorsal; epi, epiphysis; l, left; r, right.

Image published in: Walentek P et al. (2014)

Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

ddc.LLOC121395060X. laevisThroughout NF stage 33 and 34epidermis
tph1.LX. laevisThroughout NF stage 31epidermis
pineal gland
secretory epithelial cell
floor plate
ciliated cell

Image source: Published

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