ventx1.2 has 49 expression phenotype(s)
Images Sources Experiment + Assay Phenotypes Human Diseases
Fig. 7. a_c4,d, b_c4,e, c_c4,f

Sempou E et al. (2022)
Xtr Wt + K+ (20mM high)

NF10 (in situ hybridization)
Expression Phenotype
increased amount ventx1.2 expression in ventral marginal zone
decreased amount trim33 expression in ectoderm
increased amount pou5f3.3 expression in animal pole
Fig.6 e

Sempou E et al. (2022)
Xtr Wt + K+ (20mM high)

NF10-12 (RNA-Seq)
Expression Phenotype
increased amount ventx1.2 expression in whole organism
increased amount atg13 expression in whole organism
increased amount eomes expression in whole organism
increased amount foxh1 expression in whole organism
increased amount pou5f3.3 expression in whole organism
increased amount rictor expression in whole organism
increased amount smad4 expression in whole organism
increased amount sox3 expression in whole organism
Fig. 4a,b, e, f, k, l, m, n

Sempou E et al. (2022)
Xtr Wt + kcnh6 CRISPR (400pg)

NF10 (in situ hybridization)
Anatomical Phenotype
abnormal gastrulation
abnormal mesoderm
Expression Phenotype
increased amount ventx1.2 expression in embryo
absent myod1 expression in dorso-lateral marginal zone
decreased amount pou5f3.3 expression in embryo
decreased amount sox2 expression in dorsal side
decreased amount trim33 expression in animal cap
decreased amount trim33 expression in endomesoderm
increased amount pou5f3.1 expression in embryo
Fig. 5 a_c2,d, b_c2,e, c_c2,f

Sempou E et al. (2022)
Xtr Wt + kcnh6 CRISPR (400pg)

NF10 (in situ hybridization)
Expression Phenotype
increased amount ventx1.2 expression in ventral marginal zone
decreased amount trim33 expression in ectoderm
increased amount pou5f3.3 expression in animal pole
Suppl. Fig. 6 b r1_c3, r2_c3

Sempou E et al. (2022)
Xtr Wt + kcnh6 CRISPR (400pg)

NF12 (in situ hybridization)
Expression Phenotype
increased amount ventx1.2 expression in animal pole
increased amount ventx1.2 expression in ventral marginal zone
increased amount pou5f3.1 expression in embryo
Fig.4.I

Gur M et al. (2022)
Xla Wt + bmp4

NF10.25 (RT-PCR)
Anatomical Phenotype
partially ventralized embryo
Expression Phenotype
increased amount ventx1.2.L expression in embryo
decreased amount admp.L expression in the embryo
decreased amount aldh1a3.L expression in embryo
decreased amount gsc.L expression in the embryo
increased amount szl.L expression in embryo
Fig.4.I

Gur M et al. (2022)
Xla Wt + bmp4

NF11 (RT-PCR)
Anatomical Phenotype
partially ventralized embryo
Expression Phenotype
increased amount ventx1.2.L expression in embryo
decreased amount admp.L expression in the embryo
decreased amount aldh1a2.L expression in the embryo
decreased amount aldh1a3.L expression in embryo
decreased amount gsc.L expression in the embryo
increased amount szl.L expression in embryo
Fig.4.I

Gur M et al. (2022)
Xla Wt + bmp4

NF13 (RT-PCR)
Anatomical Phenotype
partially ventralized embryo
Expression Phenotype
decreased amount ventx1.2.L expression in embryo
decreased amount admp.L expression in the embryo
decreased amount aldh1a2.L expression in the embryo
decreased amount aldh1a3.L expression in embryo
decreased amount gsc.L expression in the embryo
Fig.4.H

Gur M et al. (2022)
Xla Wt + wnt8a

NF10.25 (RT-PCR)
Anatomical Phenotype
partially dorsalized embryo
Expression Phenotype
decreased amount ventx1.2.L expression in embryo
increased amount admp.L expression in the embryo
increased amount aldh1a3.L expression in the embryo
increased amount gsc.L expression in the embryo
decreased amount szl.L expression in the embryo
increased amount aldh1a2.L expression in embryo
Fig.4.H

Gur M et al. (2022)
Xla Wt + wnt8a

NF11 (RT-PCR)
Anatomical Phenotype
partially dorsalized embryo
Expression Phenotype
decreased amount ventx1.2.L expression in embryo
increased amount admp.L expression in the embryo
increased amount aldh1a3.L expression in the embryo
increased amount gsc.L expression in the embryo
decreased amount szl.L expression in the embryo
increased amount aldh1a2.L expression in embryo
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