Gagnon JA , Mowry KL .

GM071049 NIGMS NIH HHS , R01 GM071049-17 NIGMS NIH HHS , T32 GM007601-33 NIGMS NIH HHS , T32-GM07601 NIGMS NIH HHS

Adelstein, Regulation and kinetics of the actin-myosin-ATP interaction. 1980, Pubmed

Adelstein, Regulation and kinetics of the actin-myosin-ATP interaction. 1980, Pubmed
Ally, Opposite-polarity motors activate one another to trigger cargo transport in live cells. 2009, Pubmed
Aronov, Visualization of translated tau protein in the axons of neuronal P19 cells and characterization of tau RNP granules. 2002, Pubmed
Bashirullah, RNA localization in development. 1998, Pubmed , Xenbase
Berezuk, Dynactin enhances the processivity of kinesin-2. 2007, Pubmed
Besse, Translational control of localized mRNAs: restricting protein synthesis in space and time. 2008, Pubmed
Betley, Kinesin II mediates Vg1 mRNA transport in Xenopus oocytes. 2004, Pubmed , Xenbase
Bianco, Bicaudal-D regulates fragile X mental retardation protein levels, motility, and function during neuronal morphogenesis. 2010, Pubmed
Birsoy, Vg 1 is an essential signaling molecule in Xenopus development. 2006, Pubmed , Xenbase
Blangy, Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150. 1997, Pubmed
Bookwalter, Essential features of the class V myosin from budding yeast for ASH1 mRNA transport. 2009, Pubmed
Bramham, Dendritic mRNA: transport, translation and function. 2007, Pubmed
Brendza, A function for kinesin I in the posterior transport of oskar mRNA and Staufen protein. 2000, Pubmed
Bridgman, Myosin motor proteins in the cell biology of axons and other neuronal compartments. 2009, Pubmed
Bullock, Differential cytoplasmic mRNA localisation adjusts pair-rule transcription factor activity to cytoarchitecture in dipteran evolution. 2004, Pubmed
Bullock, Guidance of bidirectional motor complexes by mRNA cargoes through control of dynein number and activity. 2006, Pubmed
Bullock, Conserved signals and machinery for RNA transport in Drosophila oogenesis and embryogenesis. 2001, Pubmed
Böhl, She2p, a novel RNA-binding protein tethers ASH1 mRNA to the Myo4p myosin motor via She3p. 2000, Pubmed
Carson, Translocation of myelin basic protein mRNA in oligodendrocytes requires microtubules and kinesin. 1997, Pubmed
Cha, Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior. 2002, Pubmed
Chung, Multiple Myo4 motors enhance ASH1 mRNA transport in Saccharomyces cerevisiae. 2010, Pubmed
Clark, Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte. 1994, Pubmed
Cole, Novel heterotrimeric kinesin-related protein purified from sea urchin eggs. 1993, Pubmed , Xenbase
Condeelis, How and why does beta-actin mRNA target? 2005, Pubmed
Davidovic, The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granules. 2007, Pubmed
Deacon, Dynactin is required for bidirectional organelle transport. 2003, Pubmed , Xenbase
Delanoue, Dynein anchors its mRNA cargo after apical transport in the Drosophila blastoderm embryo. 2005, Pubmed
Delanoue, Drosophila Squid/hnRNP helps Dynein switch from a gurken mRNA transport motor to an ultrastructural static anchor in sponge bodies. 2007, Pubmed
Dictenberg, A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. 2008, Pubmed
Dienstbier, Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor. 2009, Pubmed
Duncan, The cytoplasmic dynein and kinesin motors have interdependent roles in patterning the Drosophila oocyte. 2002, Pubmed
Dunn, Myo4p is a monomeric myosin with motility uniquely adapted to transport mRNA. 2007, Pubmed
Eberwine, Analysis of subcellularly localized mRNAs using in situ hybridization, mRNA amplification, and expression profiling. 2002, Pubmed
Encalada, Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. 2011, Pubmed
Ephrussi, Oskar organizes the germ plasm and directs localization of the posterior determinant nanos. 1991, Pubmed
Falley, Shank1 mRNA: dendritic transport by kinesin and translational control by the 5'untranslated region. 2009, Pubmed
Gagnon, Directional transport is mediated by a Dynein-dependent step in an RNA localization pathway. 2013, Pubmed , Xenbase
Gill, Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. 1991, Pubmed
Gonsalvez, RNA localization in yeast: moving towards a mechanism. 2005, Pubmed
Gross, Cargo transport: two motors are sometimes better than one. 2007, Pubmed
Hamilton, RNA localization signals: deciphering the message with bioinformatics. 2007, Pubmed
Hendricks, Motor coordination via a tug-of-war mechanism drives bidirectional vesicle transport. 2010, Pubmed
Heuck, Monomeric myosin V uses two binding regions for the assembly of stable translocation complexes. 2007, Pubmed
Heuck, The structure of the Myo4p globular tail and its function in ASH1 mRNA localization. 2010, Pubmed
Hirokawa, Microtubule organization and dynamics dependent on microtubule-associated proteins. 1994, Pubmed
Hirokawa, Kinesin superfamily motor proteins and intracellular transport. 2009, Pubmed
Hirokawa, Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration. 1989, Pubmed
Hirokawa, mRNA transport in dendrites: RNA granules, motors, and tracks. 2006, Pubmed
Hodges, She3p binds to the rod of yeast myosin V and prevents it from dimerizing, forming a single-headed motor complex. 2008, Pubmed
Holt, Subcellular mRNA localization in animal cells and why it matters. 2009, Pubmed
Holzbaur, Coordination of molecular motors: from in vitro assays to intracellular dynamics. 2010, Pubmed
Janke, Tubulin post-translational modifications: encoding functions on the neuronal microtubule cytoskeleton. 2010, Pubmed
Jansen, Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins. 1996, Pubmed
Januschke, Polar transport in the Drosophila oocyte requires Dynein and Kinesin I cooperation. 2002, Pubmed
Jaramillo, The dynamics of fluorescently labeled endogenous gurken mRNA in Drosophila. 2008, Pubmed
Kanai, Kinesin transports RNA: isolation and characterization of an RNA-transporting granule. 2004, Pubmed
Kardon, Regulators of the cytoplasmic dynein motor. 2009, Pubmed
Karki, Cytoplasmic dynein and dynactin in cell division and intracellular transport. 1999, Pubmed
King, Putting RNAs in the right place at the right time: RNA localization in the frog oocyte. 2005, Pubmed , Xenbase
Krauss, Myosin-V regulates oskar mRNA localization in the Drosophila oocyte. 2009, Pubmed
Krendel, Myosins: tails (and heads) of functional diversity. 2005, Pubmed
Lan, Evidence for a transport-trap mode of Drosophila melanogaster gurken mRNA localization. 2010, Pubmed
Larsen, BicaudalD actively regulates microtubule motor activity in lipid droplet transport. 2008, Pubmed
Latham, A Rho-dependent signaling pathway operating through myosin localizes beta-actin mRNA in fibroblasts. 2001, Pubmed
Lewis, Ribonucleoprotein remodeling during RNA localization. 2007, Pubmed , Xenbase
Ling, Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein. 2004, Pubmed
Lipshitz, Mechanisms of RNA localization and translational regulation. 2000, Pubmed
Loiseau, Drosophila PAT1 is required for Kinesin-1 to transport cargo and to maximize its motility. 2010, Pubmed
Long, She2p is a novel RNA-binding protein that recruits the Myo4p-She3p complex to ASH1 mRNA. 2000, Pubmed
Long, Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA. 1997, Pubmed
MacDougall, Drosophila gurken (TGFalpha) mRNA localizes as particles that move within the oocyte in two dynein-dependent steps. 2003, Pubmed
Mach, An Egalitarian-BicaudalD complex is essential for oocyte specification and axis determination in Drosophila. 1997, Pubmed
Martin, Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport. 1999, Pubmed
Martin, mRNA localization: gene expression in the spatial dimension. 2009, Pubmed
Melton, Translocation of a localized maternal mRNA to the vegetal pole of Xenopus oocytes. , Pubmed , Xenbase
Messitt, Multiple kinesin motors coordinate cytoplasmic RNA transport on a subpopulation of microtubules in Xenopus oocytes. 2008, Pubmed , Xenbase
Mhlanga, In vivo colocalisation of oskar mRNA and trans-acting proteins revealed by quantitative imaging of the Drosophila oocyte. 2009, Pubmed
Mili, Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions. 2008, Pubmed
Minakhina, Axes formation and RNA localization. 2005, Pubmed
Müller, Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors. 2008, Pubmed
Müller, Bidirectional transport by molecular motors: enhanced processivity and response to external forces. 2010, Pubmed
Münchow, Association of the class V myosin Myo4p with a localised messenger RNA in budding yeast depends on She proteins. 1999, Pubmed
Navarro, Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate. 2004, Pubmed
Palacios, Kinesin light chain-independent function of the Kinesin heavy chain in cytoplasmic streaming and posterior localisation in the Drosophila oocyte. 2002, Pubmed
Penagarikano, The pathophysiology of fragile x syndrome. 2007, Pubmed
Poon, Identification of process-localized mRNAs from cultured rodent hippocampal neurons. 2006, Pubmed
Rayment, The three-dimensional structure of a molecular motor. 1994, Pubmed
Reck-Peterson, The yeast class V myosins, Myo2p and Myo4p, are nonprocessive actin-based motors. 2001, Pubmed
Redeker, Mass spectrometry analysis of C-terminal posttranslational modifications of tubulins. 2010, Pubmed
Schnorrer, The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes. 2000, Pubmed
Schroer, Dynactin. 2004, Pubmed
Sossin, Intracellular trafficking of RNA in neurons. 2006, Pubmed
St Johnston, Moving messages: the intracellular localization of mRNAs. 2005, Pubmed
St Johnston, Staufen, a gene required to localize maternal RNAs in the Drosophila egg. 1991, Pubmed
Sundell, Requirement of microfilaments in sorting of actin messenger RNA. 1991, Pubmed
Suzuki, Characterization of mRNA species that are associated with postsynaptic density fraction by gene chip microarray analysis. 2007, Pubmed
Takizawa, The myosin motor, Myo4p, binds Ash1 mRNA via the adapter protein, She3p. 2000, Pubmed
Tang, A role for a rat homolog of staufen in the transport of RNA to neuronal dendrites. 2001, Pubmed
Tekotte, Intracellular mRNA localization: motors move messages. 2002, Pubmed
Uchida, Tight functional coupling of kinesin-1A and dynein motors in the bidirectional transport of neurofilaments. 2009, Pubmed
Uteng, Poleward transport of Eg5 by dynein-dynactin in Xenopus laevis egg extract spindles. 2008, Pubmed , Xenbase
Vale, The molecular motor toolbox for intracellular transport. 2003, Pubmed
Vale, Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. 1985, Pubmed
Vallee, Dynein: An ancient motor protein involved in multiple modes of transport. 2004, Pubmed
Veigel, Moving into the cell: single-molecule studies of molecular motors in complex environments. 2011, Pubmed
Vessey, A loss of function allele for murine Staufen1 leads to impairment of dendritic Staufen1-RNP delivery and dendritic spine morphogenesis. 2008, Pubmed
Vicente-Manzanares, Non-muscle myosin II takes centre stage in cell adhesion and migration. 2009, Pubmed
Villacé, The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs. 2004, Pubmed
Vuppalanchi, Regulation of mRNA transport and translation in axons. 2009, Pubmed
Wang, Spatially restricting gene expression by local translation at synapses. 2010, Pubmed
Waterman-Storer, The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport. 1997, Pubmed
Wedaman, Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex. 1996, Pubmed
Weil, Distinguishing direct from indirect roles for bicoid mRNA localization factors. 2010, Pubmed
Weil, Localization of bicoid mRNA in late oocytes is maintained by continual active transport. 2006, Pubmed
Welte, Bidirectional transport along microtubules. 2004, Pubmed
Welte, Molecular motors: a traffic cop within? 2008, Pubmed
Westermann, Post-translational modifications regulate microtubule function. 2003, Pubmed
Wilkie, Drosophila wingless and pair-rule transcripts localize apically by dynein-mediated transport of RNA particles. 2001, Pubmed
Williams, Structural and thermodynamic characterization of a cytoplasmic dynein light chain-intermediate chain complex. 2007, Pubmed
Yang, A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses. 1989, Pubmed
Yoon, Xenopus Staufen is a component of a ribonucleoprotein complex containing Vg1 RNA and kinesin. 2004, Pubmed , Xenbase
Zimyanin, In vivo imaging of oskar mRNA transport reveals the mechanism of posterior localization. 2008, Pubmed