Nishanth MJ , Simon B .

SB/YS/LS-188/2014 Department of Science and Technology, Govt. of India, BT/Bio-CARe/02/10078/2013-14 Department of Biotechnology, Govt. of India, IF170376 DST-INSPIRE Fellowship, Department of Science and Technology, Govt. of India.

Abbasi, APUM23, a nucleolar Puf domain protein, is involved in pre-ribosomal RNA processing and normal growth patterning in Arabidopsis. 2010, Pubmed

Abbasi, APUM23, a nucleolar Puf domain protein, is involved in pre-ribosomal RNA processing and normal growth patterning in Arabidopsis. 2010, Pubmed
Aggarwal, Identification of novel markers for stem-cell niche of Arabidopsis shoot apex. 2010, Pubmed
Amaral, The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies). 2007, Pubmed
Arae, Identification of Arabidopsis CCR4-NOT Complexes with Pumilio RNA-Binding Proteins, APUM5 and APUM2. 2019, Pubmed
Archer, Trypanosoma brucei PUF9 regulates mRNAs for proteins involved in replicative processes over the cell cycle. 2009, Pubmed
Bernstein, Binding specificity and mRNA targets of a C. elegans PUF protein, FBF-1. 2005, Pubmed
Bhalla, Molecular control of stem cell maintenance in shoot apical meristem. 2006, Pubmed
Bohn, Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins. 2018, Pubmed
Brocard, Pumilio directs deadenylation-associated translational repression of the cyclin-dependent kinase 1 activator RGC-32. 2018, Pubmed
Campbell, Identification of a conserved interface between PUF and CPEB proteins. 2012, Pubmed
Cao, Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition. 2010, Pubmed , Xenbase
Caro, Trypanosoma cruzi: analysis of the complete PUF RNA-binding protein family. 2006, Pubmed
Carreira-Rosario, Repression of Pumilio Protein Expression by Rbfox1 Promotes Germ Cell Differentiation. 2016, Pubmed
Chen, Identification of synaptic targets of Drosophila pumilio. 2008, Pubmed
Cho, Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos. 2006, Pubmed
Chritton, A role for the poly(A)-binding protein Pab1p in PUF protein-mediated repression. 2011, Pubmed
Crittenden, A conserved RNA-binding protein controls germline stem cells in Caenorhabditis elegans. 2002, Pubmed
Cui, The malaria parasite Plasmodium falciparum encodes members of the Puf RNA-binding protein family with conserved RNA binding activity. 2002, Pubmed
Dai, PUM1 knockdown prevents tumor progression by activating the PERK/eIF2/ATF4 signaling pathway in pancreatic adenocarcinoma cells. 2019, Pubmed
Dallagiovanna, Functional genomic characterization of mRNAs associated with TcPUF6, a pumilio-like protein from Trypanosoma cruzi. 2008, Pubmed
D'Amico, The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging. 2019, Pubmed
Driscoll, Pumilio-2 regulates translation of Nav1.6 to mediate homeostasis of membrane excitability. 2013, Pubmed
Droll, The trypanosome Pumilio-domain protein PUF7 associates with a nuclear cyclophilin and is involved in ribosomal RNA maturation. 2010, Pubmed
Edwards, Structure of Pumilio reveals similarity between RNA and peptide binding motifs. 2001, Pubmed
Elguindy, PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD. 2019, Pubmed
Fiore, Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. 2009, Pubmed
Follwaczny, Pumilio2-deficient mice show a predisposition for epilepsy. 2017, Pubmed
Forbes, Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells. 1998, Pubmed
Francischini, Molecular characterization of Arabidopsis thaliana PUF proteins--binding specificity and target candidates. 2009, Pubmed
Gallie, A tale of two termini: a functional interaction between the termini of an mRNA is a prerequisite for efficient translation initiation. 1998, Pubmed
Gamberi, An anterior function for the Drosophila posterior determinant Pumilio. 2002, Pubmed
Gennarino, A Mild PUM1 Mutation Is Associated with Adult-Onset Ataxia, whereas Haploinsufficiency Causes Developmental Delay and Seizures. 2018, Pubmed
Gennarino, Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels. 2015, Pubmed
Glerum, Characterization of COX17, a yeast gene involved in copper metabolism and assembly of cytochrome oxidase. 1996, Pubmed
Glisovic, RNA-binding proteins and post-transcriptional gene regulation. 2008, Pubmed
Goldstrohm, Multifunctional deadenylase complexes diversify mRNA control. 2008, Pubmed
Goldstrohm, PUF proteins bind Pop2p to regulate messenger RNAs. 2006, Pubmed
Gorgoni, The roles of cytoplasmic poly(A)-binding proteins in regulating gene expression: a developmental perspective. 2004, Pubmed
Gu, A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization. 2004, Pubmed
Guan, PUM1 promotes ovarian cancer proliferation, migration and invasion. 2018, Pubmed
Gupta, Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity. 2008, Pubmed
Haramati, Identification and characterization of roles for Puf1 and Puf2 proteins in the yeast response to high calcium. 2017, Pubmed
Hodgman, CPEB phosphorylation and cytoplasmic polyadenylation are catalyzed by the kinase IAK1/Eg2 in maturing mouse oocytes. 2001, Pubmed , Xenbase
Hotz, Pumilio-dependent localization of mRNAs at the cell front coordinates multiple pathways required for chemotaxis. 2017, Pubmed
Houshmandi, Yeast Puf3 mutants reveal the complexity of Puf-RNA binding and identify a loop required for regulation of mRNA decay. 2005, Pubmed
Huang, Salt hypersensitive mutant 9, a nucleolar APUM23 protein, is essential for salt sensitivity in association with the ABA signaling pathway in Arabidopsis. 2018, Pubmed
Huh, APUM5, encoding a Pumilio RNA binding protein, negatively regulates abiotic stress responsive gene expression. 2014, Pubmed
Huh, Arabidopsis Pumilio protein APUM5 suppresses Cucumber mosaic virus infection via direct binding of viral RNAs. 2013, Pubmed
Inada, Novel roles of the multi-functional CCR4-NOT complex in post-transcriptional regulation. 2014, Pubmed
Ivshina, Cytoplasmic polyadenylation element binding proteins in development, health, and disease. 2014, Pubmed
Jackson, Recruitment of the Puf3 protein to its mRNA target for regulation of mRNA decay in yeast. 2004, Pubmed
Joly, The CCR4 deadenylase acts with Nanos and Pumilio in the fine-tuning of Mei-P26 expression to promote germline stem cell self-renewal. 2013, Pubmed
Kaye, A 3'UTR pumilio-binding element directs translational activation in olfactory sensory neurons. 2009, Pubmed
Kedde, A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility. 2010, Pubmed
Kopp, PUMILIO hyperactivity drives premature aging of Norad-deficient mice. 2019, Pubmed
Kuo, A novel puf-A gene predicted from evolutionary analysis is involved in the development of eyes and primordial germ-cells. 2009, Pubmed
Kurisaki, Identification and expression analysis of rainbow trout pumilio-1 and pumilio-2. 2007, Pubmed
Lee, Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins. 2016, Pubmed
Lee, Glucose-Regulated Phosphorylation of the PUF Protein Puf3 Regulates the Translational Fate of Its Bound mRNAs and Association with RNA Granules. 2015, Pubmed
Lee, Identification and gene expression profiling of the Pum1 and Pum2 members of the Pumilio family in the chicken. 2008, Pubmed
Liang, Puf3 participates in ribosomal biogenesis in malaria parasites. 2018, Pubmed
Lin, Essential requirement of mammalian Pumilio family in embryonic development. 2018, Pubmed
Lin, Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b. 2019, Pubmed
Lin, Myocyte enhancer factor-2 and p300 interact to regulate the expression of homeostatic regulator Pumilio in Drosophila. 2019, Pubmed
Lin, An RNAi-mediated screen identifies novel targets for next-generation antiepileptic drugs based on increased expression of the homeostatic regulator pumilio. 2018, Pubmed
Lin, Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis. 2017, Pubmed
Liu, Characterization of TgPuf1, a member of the Puf family RNA-binding proteins from Toxoplasma gondii. 2014, Pubmed
Liu, PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2. 2017, Pubmed
Lu, Alternate modes of cognate RNA recognition by human PUMILIO proteins. 2011, Pubmed
Lublin, The RNA-binding proteins PUF-5, PUF-6, and PUF-7 reveal multiple systems for maternal mRNA regulation during C. elegans oogenesis. 2007, Pubmed
Lynn, The PINHEAD/ZWILLE gene acts pleiotropically in Arabidopsis development and has overlapping functions with the ARGONAUTE1 gene. 1999, Pubmed
Macdonald, The Drosophila pumilio gene: an unusually long transcription unit and an unusual protein. 1992, Pubmed
Maekawa, Reduced Expression of APUM24, Encoding a Novel rRNA Processing Factor, Induces Sugar-Dependent Nucleolar Stress and Altered Sugar Responses in Arabidopsis thaliana. 2018, Pubmed
Malik, The target specificity of the RNA binding protein Pumilio is determined by distinct co-factors. 2019, Pubmed
Mee, Regulation of neuronal excitability through pumilio-dependent control of a sodium channel gene. 2004, Pubmed
Menon, The translational repressor Pumilio regulates presynaptic morphology and controls postsynaptic accumulation of translation factor eIF-4E. 2004, Pubmed
Menon, The translational repressors Nanos and Pumilio have divergent effects on presynaptic terminal growth and postsynaptic glutamate receptor subunit composition. 2009, Pubmed
Miao, The Puf-family RNA-binding protein PfPuf2 regulates sexual development and sex differentiation in the malaria parasite Plasmodium falciparum. 2010, Pubmed
Miles, Pumilio facilitates miRNA regulation of the E2F3 oncogene. 2012, Pubmed
Miles, Alternative Polyadenylation in Triple-Negative Breast Tumors Allows NRAS and c-JUN to Bypass PUMILIO Posttranscriptional Regulation. 2016, Pubmed
Miller, Roles of Puf proteins in mRNA degradation and translation. 2011, Pubmed
Moore, Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins. 2003, Pubmed
Muraro, Pumilio binds para mRNA and requires Nanos and Brat to regulate sodium current in Drosophila motoneurons. 2008, Pubmed
Murata, Binding of pumilio to maternal hunchback mRNA is required for posterior patterning in Drosophila embryos. 1995, Pubmed
Nakahata, Involvement of Xenopus Pumilio in the translational regulation that is specific to cyclin B1 mRNA during oocyte maturation. 2003, Pubmed , Xenbase
Naudin, PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells. 2017, Pubmed
Nolde, The Caenorhabditis elegans pumilio homolog, puf-9, is required for the 3'UTR-mediated repression of the let-7 microRNA target gene, hbl-1. 2007, Pubmed
Nyikó, Functional and molecular characterization of the conserved Arabidopsis PUMILIO protein, APUM9. 2019, Pubmed
Padmanabhan, Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation. 2006, Pubmed , Xenbase
Parisi, The Drosophila pumilio gene encodes two functional protein isoforms that play multiple roles in germline development, gonadogenesis, oogenesis and embryogenesis. 1999, Pubmed
Qiu, A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization. 2014, Pubmed
Qiu, Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity. 2019, Pubmed
Richter, Regulation of cap-dependent translation by eIF4E inhibitory proteins. 2005, Pubmed
Ryder, Pumilio RNA recognition: the consequence of promiscuity. 2011, Pubmed
Sajek, PUM1 and PUM2 exhibit different modes of regulation for SIAH1 that involve cooperativity with NANOS paralogues. 2019, Pubmed
Salvetti, DjPum, a homologue of Drosophila Pumilio, is essential to planarian stem cell maintenance. 2005, Pubmed
Shanmugam, An Arabidopsis divergent pumilio protein, APUM24, is essential for embryogenesis and required for faithful pre-rRNA processing. 2017, Pubmed
Shigunov, PUMILIO-2 is involved in the positive regulation of cellular proliferation in human adipose-derived stem cells. 2012, Pubmed
Siemen, Pumilio-2 function in the mouse nervous system. 2011, Pubmed
Somssich, CLAVATA-WUSCHEL signaling in the shoot meristem. 2016, Pubmed
Sonoda, Drosophila Brain Tumor is a translational repressor. 2001, Pubmed
Spassov, Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins. 2002, Pubmed
Spassov, The PUF family of RNA-binding proteins: does evolutionarily conserved structure equal conserved function? 2003, Pubmed
Tadauchi, Post-transcriptional regulation through the HO 3'-UTR by Mpt5, a yeast homolog of Pumilio and FBF. 2001, Pubmed
Tam, The Puf family of RNA-binding proteins in plants: phylogeny, structural modeling, activity and subcellular localization. 2010, Pubmed
Tichon, SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA. 2018, Pubmed
Vaidyanathan, Pseudouridine and N6-methyladenosine modifications weaken PUF protein/RNA interactions. 2017, Pubmed
Van Etten, Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs. 2012, Pubmed
van Kouwenhove, MicroRNA regulation by RNA-binding proteins and its implications for cancer. 2011, Pubmed
Vessey, Mammalian Pumilio 2 regulates dendrite morphogenesis and synaptic function. 2010, Pubmed
Walser, Distinct roles of the Pumilio and FBF translational repressors during C. elegans vulval development. 2006, Pubmed
Wang, Crystal structure of a Pumilio homology domain. 2001, Pubmed
Wang, Modular recognition of RNA by a human pumilio-homology domain. 2002, Pubmed , Xenbase
Wang, Novel insights into global translational regulation through Pumilio family RNA-binding protein Puf3p revealed by ribosomal profiling. 2019, Pubmed
Webster, RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not. 2019, Pubmed
Weidmann, Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio. 2016, Pubmed
Weidmann, Drosophila Pumilio protein contains multiple autonomous repression domains that regulate mRNAs independently of Nanos and brain tumor. 2012, Pubmed
Wreden, Nanos and pumilio establish embryonic polarity in Drosophila by promoting posterior deadenylation of hunchback mRNA. 1997, Pubmed
Xiang, Reduced Dormancy5 encodes a protein phosphatase 2C that is required for seed dormancy in Arabidopsis. 2014, Pubmed
Ye, Nanos and Pumilio are essential for dendrite morphogenesis in Drosophila peripheral neurons. 2004, Pubmed
Zhang, Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins. 2017, Pubmed
Zhang, A Nucleolar PUF RNA-binding Protein with Specificity for a Unique RNA Sequence. 2015, Pubmed
Zhang, Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA. 2016, Pubmed
Zhang, A conserved RNA-binding protein that regulates sexual fates in the C. elegans hermaphrodite germ line. 1997, Pubmed
Zhao, Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis. 1999, Pubmed
Zoncu, mTOR: from growth signal integration to cancer, diabetes and ageing. 2011, Pubmed