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Histochem Cell Biol 2007 Feb 01;1272:139-48. doi: 10.1007/s00418-006-0231-0.
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Nuclear myosin is ubiquitously expressed and evolutionary conserved in vertebrates.

Kahle M , Pridalová J , Spacek M , Dzijak R , Hozák P .

Nuclear myosin I (NMI) is a single-headed member of myosin superfamily localized in the cell nucleus which participates along with nuclear actin in transcription and chromatin remodeling. We demonstrate that NMI is present in cell nuclei of all mouse tissues examined except for cells in terminal stages of spermiogenesis. Quantitative PCR and western blots demonstrate that the expression of NMI in tissues varies with the highest levels in the lungs. The expression of NMI is lower in serum-starved cells and it increases after serum stimulation. The lifespan of NMI is longer than 16 h as determined by cycloheximide translation block. A homologous protein is expressed in human, chicken, Xenopus, and zebrafish as shown by RACE analysis. The analysis of genomic sequences indicates that almost identical homologous NMI genes are expressed in mammals, and similar NMI genes in vertebrates.

PubMed ID: 16957816
Article link: Histochem Cell Biol

Species referenced: Xenopus
Genes referenced: actl6a cyp26a1 myo1c nmi

References [+] :
Altschul, Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. 1997, Pubmed