Figure 8. Current–variance relationships of IKs channels formed with S74L and D76N minK subunits. (A) Family of currents recorded from a patch excised from an oocyte coinjected with KvLQT1 cRNA and a 1:1 mixture of D76N and S74L minK cRNAs. The patch was clamped at −60 mV and depolarized from −20 to 100 mV in 10-mV steps. (B) Current–voltage relationship of peak tail currents measured for channels, mean ± SEM for three separate patches. (C) Current–variance relationship computed from the patch in A; the conductance calculated in this patch was 6.0 pS.
Image published in: Sesti F and Goldstein SA (1998)
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