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Figure 21. (A and B) Time constants from single exponential fits to interburst closed time distributions for R177Q (□) and R176L (▵) currents are plotted as functions of voltage (□). Interburst duration distribution time constants from wild-type KAT1 currents are superimposed (○). (C and D) The time constants from single exponential fits to the within-burst closed time distributions for R177Q (□) and R176L (▵) currents are plotted as functions of voltage. Corresponding time constants from wild-type KAT1 currents are superimposed (○). (E and F) The probability of terminating a burst (q) derived from geometric fits to the distributions of the number of openings per burst is plotted as functions of voltage for R177Q (□) and R176L (▵) currents. Corresponding data for wild-type KAT1 currents are superimposed for comparison. A burst criterion of 20 ms was used in all analysis in this figure.

Image published in: Zei PC and Aldrich RW (1998)

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