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Larger Image Figure 3. Bursting kinetics for wild-type mSlo1 channels differ from wild-type mSlo3 channels at comparable PO's. (A–D) Plots of the indicated mean bursting parameters for each channel type. Compared with mSlo1 channels, mSlo3 channels showed a briefer mean burst duration (P < 0.01), a briefer mean open time (P < 0.001), and a briefer mean gap duration between bursts (P < 0.02), while showing no significant difference in the mean number of openings per burst (P = 0.5). Error bars represent SEM. Data were obtained from five patches containing mSlo1 channels and five patches containing mSlo3 channels. Mean PO: mSlo1 = 0.030 ± 0.005 (range: 0.014–0.040); mSlo3 = 0.030 ± 0.009 (range: 0.011–0.055). All data were obtained at a Ca2+i of 0 μM and a membrane potential of +80 mV. Image published in: Moss BL and Magleby KL (2001) © 2001 The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license Permanent Image Page Printer Friendly View XB-IMG-121141 |