Figure 5. Single-channel records of ENaC wt and αS589 mutants. Traces are from outside-out patches from Xenopus oocytes at a holding potential of −100 mV in extracellular Li+ solution. The dotted lines indicate the baseline when all ENaC channels in the patch are closed. The outside-out configuration was chosen to verify amiloride-sensitivity of channel activity.
Image published in: Kellenberger S et al. (2001)
© 2001 The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license
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