Figure 3. . Sub-Schemes derived from Scheme II. Under extreme conditions that limit Ca2+-binding, voltage sensor activation, or channel opening, the number of interactions that govern mSlo1 gating is reduced and Scheme II is reduced to the following subschemes. (A) unliganded, (B) Ca2+-saturated, (C) very negative voltages (voltage sensors resting), (D) very positive voltages (voltage sensors activated), (E) closed, and (F) open.
Image published in: Horrigan FT and Aldrich RW (2002)
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