Figure 4. . Effects of a double mutation (E224G+E299S) in the COOH terminus on the voltage-dependent block of IRK1 current by polyamines. The fraction of mutant channel currents (mean ± SEM; n = 4–6) not blocked by PUT, SPD, or SPM (at the concentrations indicated) is plotted against membrane voltage. The curves fitted to the data are described in results.
Image published in: Guo D and Lu Z (2003)
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