Figure 1. Qualitative effects of S(−)-CPB on the ClC-0 mutant C212S. (A–C) Family of voltage clamp traces recorded from one inside-out patch expressing the point mutant C212S of ClC-0. Currents were elicited using the pulse protocol shown in the inset. The concentration of intracellularly applied S(−)-CPB is indicated. (D) The apparent open probability (symbols) obtained from the initial current at the −100 mV tail pulse (see materials and methods) together with fits of to the data (solid lines).
Image published in: Pusch M et al. (2001)
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