Figure 4. The β1 subunit shifts the closed channel's charge–voltage (Q–V) relation leftward without changing its shape. (A) On and Off Q–V relations determined from a single BKα channel patch. (B) On and Off Q–V relations determined from a single BKα+β1 channel patch. (C) Normalized averaged Qon–V relations for the BKα (11 curves averaged) and BKα+β1 channels (14 curves averaged). Each curve in C is fitted with a Boltzmann function. The fit parameters are as follows: BKα: zJ = 0.577 ± 0.023e, Vhc = 151 ± 1.9 mV; BKα+β1: zJ = 0.571 ± 0.025 e, Vhc = 80 ± 2.4 mV. The error bars in C represent SEM.
Image published in: Bao L and Cox DH (2005)
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