Fig. 5. Sensitivity to MgADP of wild-type and hetL164P channels. a Representative currents (I) recorded at −60 mV from inside-out excised membrane patches from Xenopus oocytes expressing wild-type or hetL164P channels, as indicated. Patches were exposed to 100 μmol/l ADP in the continuous presence of 100 μmol/l ATP: 2 mmol/l Mg2+ was present throughout. b Mean current in the presence of 100 μmol/l MgATP or 30 or 100 μmol/l MgADP plus 100 μmol/l MgATP, normalised to the current in the absence of nucleotides for wild-type (grey bars) and hetL164P (black bars) channels. Bars indicate means ± SEM. The number of patches was three to four in each case
Image published in: Tammaro P et al. (2008)
Image downloaded from an Open Access article in PubMed Central. © The Author(s) 2008
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