Larger Image Figure 4. Comparison of verapamil-inhibitable Isc levels in H441 monolayers when applied to the apical or basolateral compartments. (A-C) Representative Isc traces showing the effects of water (H2O), verapamil applied to basolateral (B) and apical (C) compartments. The total AS Isc levels associated with ENaC are designated by pairs of vertical arrows. (D) AS Isc levels before and after verapamil delivery to the basolateral side or apical compartment. Paired t-test for comparison of current levels before and after verapamil. *P < 0.05 and **P < 0.01. n = 4-17. Image published in: Han DY et al. (2010) Copyright ©2010 Han et al; licensee BioMed Central Ltd. Creative Commons Attribution license Permanent Image Page Printer Friendly View XB-IMG-125028 |