Figure 3. Polycystin-1 product CTF does not inhibit SOCE.(A) Western blot of PC1 cleavage product constructs P100 and CTF expressed in Xenopus oocytes, immunoprecipitated with flag conjugated beads and probed with anti-CT antibody. (B) Averaged currents elicited by a −120 mV voltage step in H2O injected control oocytes (black trace, n = 20) or from oocytes expressing CTF (red trace, n = 14). (C) Mean current amplitudes at the transient peak and steady state. ±SEM.
Image published in: Woodward OM et al. (2010)
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