Figure 8. Model of cHES6-1 and cHES6-2 function during neurogenesis.During neuronal differentiation in the developing spinal cord, cHES6-1 and cHES6-2 act sequentially to relieve the cell from Notch signalling: cHES6-2 acts first to repress the transcription of cHes5 genes and cHES6-1 subsequently sequesters and inactivates cHES5 and cHES6-2 proteins.
Image published in: Vilas-Boas F and Henrique D (2010)
Vilas-Boas, Henrique. Creative Commons Attribution license
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