Fig. 5. IRE1α knockdown inhibits the expression of specification marker genes.Whole mount in situ hybridization analyses revealed that the expression of pdx1 (B) and ptf1α (D) was significantly suppressed in IRE1α MO injected embryos at stage 30 compared with control MO injected embryos (A, C). The white arrows indicate positive staining.
Image published in: Yuan L et al. (2014)
Image downloaded from an Open Access article in PubMed Central. © 2014 by the Journal of Biomedical Research. All rights reserved.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| pdx1.L | ipf1, pdx-1, STF-1, XlHbox-8, XlHbox8 | X. laevis | Throughout NF stage 29 and 30 | pancreas anterior endoderm |
| ptf1a.L | ptf1a-a, ptf1a-b, Ptf1a/p48, XPtf1a | X. laevis | Throughout NF stage 29 and 30 | pancreas anterior endoderm hindbrain floor plate |
Image source: Published
| Experiment + Assay | Source | Phenotypes and Disease |
|---|---|---|
| Xla Wt + ern1 MO + NF 30 | Fig. 5 C D |
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