Fig. 7. Expression of HNK-1 by Rohon-Beard neurons in normal and RA-treated embryos. Panel A shows the pattern of expression of the HNK-1 antigen in wholemount preparations of tadpole stage (stage â38-40) embryos. mAb HNK-1 labels a variety of structures in the CNS including the cell bodies of Rohon-Beard neurons in the dorsal spinal cord (arrowheads). Panel B shows the labelling pattern of HNK-1 in the spinal cord of an embryo treated with high concentrations of RA. The inhibition of normal anterior development is not accompanied by an anterior extension of the domain over which Rohon-Beard neurons appear (bracket). Cg, cement gland; HB, hindbrain; o, otic vesicle; RA, embryo treated with high (H-RA) concentration of RA; SC, spinal cord. Scale bar=0.5mm.
Image published in: Ruiz i Altaba A and Jessell TM (1991)
Copyright © 1991. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| b3gat1l.L | cd57, glcatp, glcuatp, hnk-1, hnk1, leu7, nk-1, nk1 | X. laevis | Sometime during NF stage 37 and 38 to NF stage 40 | spinal cord spinal nerve eye cranial nerve trigeminal nerve facial nerve |
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