Larger Image Figure 6. Combined Loss of Eomes, VegT, and Xbra Reveals Their Collaboration to Determine Neuromesodermal Bipotency and Promote Mesodermal Differentiation during Axial ElongationGastrula-staged snapshots of Eomes, VegT, and Xbra binding near mesoderm-specific genes myf5, myoD, msgn1, foxc1, mespa (A, B, and D–F), and neurogenic genes sox3 and pax3 (G and H). WMISH on control and indicated KD embryos for target genes (A, B, and D–H) and muscle-specific differentiation marker myosin heavy chain 1, myh1 (C). Cross-sections at positions of sox3 and pax3 WMISH as indicated. no, notochord; nt, neural tube (d, dorsal; v, ventral); hm, hypaxial muscle; pm, paraxial mesoderm; sm, skeletal muscle. The scale bar represents 0.2 mm. See also Figures S6 and S7. Image published in: Gentsch GE et al. (2013) © 2013 The Authors. Creative Commons Attribution license Permanent Image Page Printer Friendly View XB-IMG-130643