Figure 3. Activity of fraction 4 on fetal muscle nAChR expressed in X. laevis oocytes. Concentration-response effects can be compared through the various panels. Arrows indicate the first current elicited after the 5 min static bath of toxin equilibration. Control membrane depolarisations elicited by 1–5 μM ACh pulses are indicated as 10% of total value (nA); (A) 1.5 μg total protein of fraction 4 inhibited 25% of ACh-elicited currents; (B) 3 μg total protein of fraction 4 blocked 50% of ACh currents; (C) 4.5 μg total protein of fraction 4 caused 96% blocking effect.
Image published in: Ponce D et al. (2013)
© 2013 by the authors; licensee MDPI, Basel, Switzerland. Creative Commons Attribution license
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