Fig. S1. Developmental expression of Tmod and Lmod family proteins at the neurula stage prior to skeletal muscle assembly. Tmod (B-D) and Lmod (E-H) family gene expression was analyzed using in situ hybridization. All embryos are positioned with heads to the left. Expression patterns were analyzed at the neurula stage (st15), before the onset of myofibrillogenesis. Expression of the striated muscle marker, cardiac actin, actna1 (A) was used to indicate skeletal muscle tissue in the embryo. Arrows indicate developing skeletal muscle in the somites. Only lmod3 (D) and tmod4 (H) are expressed at high levels in developing skeletal muscle.
Image published in: Nworu CU et al. (2015)
Copyright © 2015. Image reproduced with permission of the Publisher, The Company of Biologists Ltd.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| actc1.L | actc, actna1, cardiac actin, cardiac alpha actin, muscle actin | X. laevis | Throughout NF stage 15 | paraxial mesoderm presomitic mesoderm |
| tmod1.L | LOC108706915 | X. laevis | Throughout NF stage 15 | |
| tmod2 | X. tropicalis | Throughout NF stage 15 | ||
| tmod3.S | X. laevis | Throughout NF stage 15 | ||
| tmod4.L | sk-tropomodulin | X. laevis | Throughout NF stage 15 | paraxial mesoderm presomitic mesoderm |
| lmod1.L | X. laevis | Throughout NF stage 15 | ||
| lmod2.L | LOC108711149, LOC108713095 | X. laevis | Throughout NF stage 15 | |
| lmod3.L | LOC108714721, LOC108715918 | X. laevis | Throughout NF stage 15 | paraxial mesoderm presomitic mesoderm |
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