Figure 4. mZIP impairs maintenance of retinotectal synapses in vivo. A, Representative immunostaining of the tectal neuropil from a horizontal brain section with antibodies against SNAP-25 (red) and PSD-95 (green) 4 h after tectal infusion of vehicle (control) and mZIP. Yellow puncta represent the overlap of SNAP-25 and PSD-95 puncta. Scale bars, 1 μm. B, C, Quantitative analysis of the density of SNAP-25 puncta, PSD-95 puncta, and juxtaposed puncta (B), as well as colocalization probability (C), normalized by the average value of the corresponding controls (n = 5 tadpoles for each condition; *p < 0.05).
Image published in: Liu XF et al. (2009)
Copyright © 2009. OA ARTICLE, images redisplayed under a Creative Commons license.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| snap25.L | ric-4, ric4, sec9, snap-25 | X. laevis | Throughout NF stage 47 | brain optic tectum neuropil of the optic tectum |
| dlg4.L | LOC108703559, LOC108711809, psd-95, psd95, sap-90, sap90 | X. laevis | Throughout NF stage 47 | brain optic tectum neuropil of the optic tectum |
Image source: Published
Permanent Image Page
Printer Friendly View
XB-IMG-149271