Larger Image Fig. 3. prdm12 knockdown in Xenopus dramatically reduces the V1 marker en1 and affects gene expression in ventral spinal cord progenitors. (A-F) Transverse sections at the neural tube of stage 32 embryos unilaterally injected with 20†ng of Prdm12 MO and hybridized as indicated. The disappearance of the gap between nkx6-1 and dbx1 expression in Prdm12 morphants is indicated by an arrow. IS, injected side. Image published in: Thélie A et al. (2015) Copyright © 2015. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue en1.L en-1, en1-a, en1-b, eng1, engrailed 1, engrailed-1, xen1 X. laevis Throughout NF stage 32 spinal cord evx1.L eve1, Xhox3 X. laevis Throughout NF stage 32 spinal cord pax6.L an2, mgda, pax-6, pax6-a, pax6-b, wagr, XLPAX6, xpax6 X. laevis Throughout NF stage 32 spinal cord nkx6-1.L LOC108704117, nkx6.1 X. laevis Throughout NF stage 32 spinal cord dbx1.S dbx, Xdbx X. laevis Throughout NF stage 32 spinal cord Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + prdm12 MO + NF28 (in situ hybridization) Fig.3.d Expression Phenotype increased amount evx1.L expression in spinal cord Xla Wt + prdm12 MO + NF28 (in situ hybridization) Fig.3.f Expression Phenotype mislocalised nkx6-2.L expression in spinal cord increased amount nkx6-2.L expression in spinal cord Permanent Image Page Printer Friendly View XB-IMG-151778