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Figure 1. Overview of the evolutionary method used to discover a novel vascular disrupting agent.Strict reliance on the evolutionary conservation of the relevant gene module allowed for an experimental design exploiting the unique experimental advantages of each model organism, thus speeding the search for novel angiogenesis inhibitors. (Vector female silhouette under Creative Commons Attribution 2.0 from ‘Keep Fit’ Vector Pack, Blog.SpoonGraphics.)

Image published in: Cha HJ et al. (2012)

Image reproduced on Xenbase with permission of the publisher and the copyright holder. Creative Commons Attribution license

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