Figure 7. Effects of human ccl19 and ccl21 on early Xenopus development. (a) Phenotypes of embryos injected with human ccl19 and ccl21 mRNA (500 pg/blastomere) (st. 28). All dorsally injected embryos showed gastrulation defects (n = 43, human ccl19 injection, and n = 44, human ccl21.L injection). All ventrally injected embryos showed ventral gastrulation defects with small secondary axis-like structures (n = 44, human ccl19 injection, and n = 43, human ccl21.L injection). Arrowheads indicate small secondary axis-like structures. Bars, 1.0 mm. (b and c) RT-PCR analysis of the dorsal or ventral sectors (st. 10) (b) and the animal caps (st. 9.5) (c) of embryos injected with human ccl19 and ccl21 mRNA.
Image published in: Goto T et al. (2023)
Copyright © 2023. Image reproduced with permission of the Publisher, John Wiley & Sons.
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