Larger Image Figure 2. etv2 is expressed in hematopoietic and endothelial precursor cells in the Xenopus embryo. A-F prime : Transcripts of etv2 (A-F) and flk1 (A prime -F prime ) were detected by in situ hybridization. flk1 is an established marker of the hematopoietic and endothelial lineages. Developmental stage of the embryos is indicated at the lower right of each panel. Embryos shown in A,A prime ,C,C prime , and insets in D,D prime are ventral views. All other views are lateral with anterior to the left. vbi, ventral blood island; pcv, posterior cardinal vein; plx, vascular plexus; isv, intersegmental vessel; rls, rostral lymphatic sac. Image published in: Salanga MC et al. (2010) Copyright © 2010. Image reproduced with permission of the Publisher, John Wiley & Sons.Gene Synonyms Species Stage(s) Tissue etv2.L er71, ets1, ets2-like, Etsrp, etsrp71 X. laevis Throughout NF stage 16 ventral blood island ventral hematopoietic stem cell kdr.L flk-1, flk1, LOC108698463, vegfr-2, vegfr2, xflk-1 X. laevis Throughout NF stage 16 vascular endothelium hematopoietic stem cell ventral blood island anterior etv2.L er71, ets1, ets2-like, Etsrp, etsrp71 X. laevis Throughout NF stage 22 ventral blood island vascular endothelium branchial arch neural crest posterior cardinal vein head region kdr.L flk-1, flk1, LOC108698463, vegfr-2, vegfr2, xflk-1 X. laevis Throughout NF stage 22 posterior cardinal vein ventral blood island vascular endothelium circulatory system hematopoietic stem cell branchial arch neural crest etv2.L er71, ets1, ets2-like, Etsrp, etsrp71 X. laevis Throughout NF stage 29 and 30 posterior cardinal vein branchial arch neural crest ventral blood island posterior head region vascular endothelium circulatory system vascular plexus kdr.L flk-1, flk1, LOC108698463, vegfr-2, vegfr2, xflk-1 X. laevis Throughout NF stage 29 and 30 branchial arch neural crest posterior cardinal vein vascular endothelium circulatory system head region heart primordium vascular plexus etv2.L er71, ets1, ets2-like, Etsrp, etsrp71 X. laevis Throughout NF stage 33 and 34 blood branchial arch posterior cardinal vein vein blood vessel circulatory system tail region tail vein vascular endothelium anterior lymph sac vascular plexus intersomitic vessel kdr.L flk-1, flk1, LOC108698463, vegfr-2, vegfr2, xflk-1 X. laevis Throughout NF stage 33 and 34 branchial arch vascular endothelium tail region intersomitic vessel vascular plexus dorsal lateral plate mesoderm head vasculature etv2.L er71, ets1, ets2-like, Etsrp, etsrp71 X. laevis Throughout NF stage 39 anterior lymph sac tail region head region vascular endothelium kdr.L flk-1, flk1, LOC108698463, vegfr-2, vegfr2, xflk-1 X. laevis Throughout NF stage 39 posterior cardinal vein anterior lymph sac circulatory system lymph vessel blood vessel head region tail vein vascular plexus
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