Supplementary Figure S1. The silver [pmel] gene is specifically expressed in the developing eye at tailbud stages. A. Wholemount in situ hybridization of late tailbud stage embryo (st 34) using silver antisense riboprobe. Silver is expressed in the eye. B. The embryos shown in (A) was embedded in paraffin and sectioned. The in situ hybridization signal is localized to the outer layer of the eye, the retinal pigmented epithelium (RPE). C. In situ hybridization performed using sections of a paraffin-embedded st 41 tadpole. Expression of the silver gene (blue color) is restricted to the RPE (brown color)[in the] lens.
Image published in: Pan Y et al. (2010)
Copyright © 2010. Image reproduced with permission of the Publisher, Elsevier B. V.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| pmel.S | gp100, me20, pmel17, pmel-a, pmel-b, sil, silver | X. laevis | Sometime during NF stage 33 and 34 to NF stage 41 | eye lens retinal pigmented epithelium pineal gland anterior ectoderm cement gland |
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