Fig. 1. Expression of Arg during early Xenopus development. A) Schematic representation of sequence alignment between human and Xenopus Arg proteins. The SH2, SH3 and tyrosine kinase domains are over 92% identical, while the actin binding domains (BDs) are 74â76% identical between the two proteins. B) Temporal expression of Arg assayed by RT-PCR (25 cycles) showed that Arg was expressed maternally and its transcripts persisted till at least tailbud stages. C) Spatial expression of Arg assayed by in situ hybridization of gastrula (panels a and b), neurula (panel c), tailbud (panels d and e) and early tadpole (panel f) embryos. The orientations of the embryos are: panel a, side view with dorsal to the right; panel b, vegetal view with dorsal to the right; panels c and e, dorsal view with anterior to the left; panels d and f, side view with anterior to the left.
Image published in: Bonacci G et al. (2012)
Copyright © 2012. Image reproduced with permission of the Publisher, Elsevier B. V.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| abl2.L | abll, arg | X. laevis | Throughout NF stage 10.25 | mesoderm dorsal marginal zone animal hemisphere neuroectoderm |
| abl2.L | abll, arg | X. laevis | Throughout NF stage 11 | mesoderm dorsal marginal zone neuroectoderm vegetal hemisphere |
| abl2.L | abll, arg | X. laevis | Throughout NF stage 17 | neural crest neural plate neuroectoderm |
| abl2.L | abll, arg | X. laevis | Throughout NF stage 22 | neural crest mesoderm head brain pronephric mesenchyme optic vesicle otic placode migratory neural crest cell neural tube neural fold |
| abl2.L | abll, arg | X. laevis | Throughout NF stage 28 | spinal cord neural crest tail bud pronephric mesenchyme pronephric duct pharyngeal region migratory neural crest cell eye otic vesicle central nervous system brain |
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