Fig.4. Expression of α-neurexins is predominantly in neural tissue in the tailbud embryo. (A,B) In situ hybridisation with a nrxn Iα probe showing whole embryo (A) and an anterior neural section (B). Nrxn I is found in cells along the length of the CNS but with a distinct gap at the midbrain-hindbrain boundary. Sections show expression in the dorsolateral neural tube and within the eye. (C,D) Embryos hybridised with a nrxn IIα-specific probe show a similar pattern of staining to that seen with nrxn I. (E,F) Embryos hybridised with a nrxn IIIα-specific probe show much more restricted expression in the CNS and in section show ventrolateral and eye expression in the anterior CNS (arrows).
Image published in: Zeng Z et al. (2006)
Copyright © 2006. Image reproduced with permission of the Publisher.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| nrxn1 | LOC108716082, LOC108717747 | X. tropicalis | Throughout NF stage 32 | spinal cord neural tube central nervous system neuron eye brain forebrain midbrain hindbrain retina |
| nrxn2.L | LOC108713967, LOC108715117 | X. laevis | Throughout NF stage 32 | forebrain hindbrain spinal cord neural tube central nervous system neuron eye brain midbrain retina |
| nrxn3.L | LOC108699836 | X. laevis | Throughout NF stage 32 | forebrain hindbrain spinal cord central nervous system eye retina brain midbrain |
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