Xla Wt + Hsa.RAF1 has 3 phenotype(s)

Images

Sources

Experiment + Assay

Phenotypes

Human Diseases

Fig. 2 D r1c2

Wong S et al. (2023)

Xla Wt + Hsa.RAF1

NF10.5 (in situ hybridization)

Expression Phenotype
increased amount tbxt.L expression in marginal zone

Fig. 2E r1c2, r2c2

Wong S et al. (2023)

Xla Wt + Hsa.RAF1

NF28 (in situ hybridization)

Anatomical Phenotype
abnormal spinal cord morphology duplicated tail

Expression Phenotype
increased amount tbxt.L expression in anterior neural tube mislocalised tbxt.L expression in chordoneural hinge mislocalised tbxt.L expression in tail tip mislocalised tubb2b.L expression in ventral side

Fig.2 C r1c2

Wong S et al. (2023)

Xla Wt + Hsa.RAF1

NF28 (whole-mount microscopy)

Anatomical Phenotype
abnormal caudal presomitic mesoderm morphology abnormal main body axis abnormal mesoderm abnormal tail bud morphology duplicated tail