tbx1 has 7 expression phenotype(s)
Images Sources Experiment + Assay Phenotypes Human Diseases
Fig 5FGH

Griffin C et al. (2025)
Xtr Wt + sf3b4 CRISPR

NF35/36 (RNA-Seq)
Anatomical Phenotype
decreased cell migration in cranial neural crest
Expression Phenotype
decreased amount tbx1 expression in whole organism
absent eftud2 expression in whole organism
absent mmp7 expression in whole organism
absent phf5a expression in whole organism
absent sf3b3 expression in whole organism
decreased amount adamts1 expression in whole organism
decreased amount ednrb expression in whole organism
decreased amount sema4c expression in whole organism
Fig. 4 C

Shah AM et al. (2020)
Xla Wt + six1

NF28-32 (in situ hybridization)
Expression Phenotype
decreased amount tbx1.L expression in otic vesicle
increased amount tbx1.L expression in otic vesicle
branchiootorenal syndrome
branchiootic syndrome
Fig. 4 C

Shah AM et al. (2020)
Xla Wt + six1

NF28-32 (in situ hybridization)
Expression Phenotype
decreased amount tbx1.L expression in otic vesicle
branchiootic syndrome
branchiootorenal syndrome
fig. 4 C

Shah AM et al. (2020)
Xla Wt + six1-R110W

NF28-32 (in situ hybridization)
Expression Phenotype
decreased amount tbx1.L expression in otic vesicle
increased amount tbx1.L expression in otic vesicle
branchiootorenal syndrome
branchiootic syndrome
Fig. 4 C

Shah AM et al. (2020)
Xla Wt + six1-V17E

NF28-32 (in situ hybridization)
Expression Phenotype
decreased amount tbx1.L expression in otic vesicle
branchiootic syndrome
branchiootorenal syndrome
Fig. 4 C, Fig. 5 F

Shah AM et al. (2020)
Xla Wt + six1-W122R

NF28-32 (in situ hybridization)
Expression Phenotype
decreased amount tbx1.L expression in otic vesicle
branchiootorenal syndrome
branchiootic syndrome
Fig. 4 C

Shah AM et al. (2020)
Xla Wt + Six1-Y129C

NF28-32 (in situ hybridization)
Expression Phenotype
decreased amount tbx1.L expression in otic vesicle
branchiootorenal syndrome
branchiootic syndrome