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XB-PHENO-27261

Xtr Wt + sf3b4 CRISPR, Griffin C et al. (2025)

Experiment + Assay: Xtr Wt + sf3b4 CRISPR + NF35/36 (RNA-Seq)
Background: Xtr.Nigerian1NXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR sf3b4 gRNA1 sf3b4
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
RNA-Seq NF stage 35 and 36  
Anatomical Phenotypes: decreased cell migration in cranial neural crest
Expression Phenotypes (8):
decreased amount adamts1 expression in whole organism
decreased amount ednrb expression in whole organism
absent eftud2 expression in whole organism
absent mmp7 expression in whole organism
absent phf5a expression in whole organism
decreased amount sema4c expression in whole organism
absent sf3b3 expression in whole organism
decreased amount tbx1 expression in whole organism
Source: Fig 5FGH
Article: XB-ART-61310, PubMed