Disease: situs inversus

Definition: A visceral heterotaxy that is characterized by complete right-to-left reversal of the position of the major thoracic and abdominal organs.

Synonyms: Complete transposition, Complete transposition (morphologic abnormality), Laterality sequence, Laterality sequence (disorder), situs inversus viscerum, situs inversus viscerum (disorder)

OMIM: MIM:270100

Reagents:

Morpholino	Experiments
cfap53 MO1	Xla Wt + cfap53 MO Xla Wt + cfap53 MO Xla Wt + cfap53 MO Xla Wt + cfap53 MO
foxj1 MO1	Xla Wt + foxj1 MO
fto MO1	Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO + actinomycin D + animal cap explant

gRNA	Experiments
kcnh6 gRNA1	Xtr Wt + kcnh6 CRISPR (400pg) Xtr Wt + kcnh6 CRISPR (400pg)

Chemical	Experiments
actinomycin D	Xla Wt + fto MO + actinomycin D + animal cap explant