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XB-PHENO-25702

Xtr Wt + kcnh6 CRISPR (400pg), Sempou E et al. (2022)

Experiment + Assay: Xtr Wt + kcnh6 CRISPR (400pg) + NF45 (whole-mount microscopy)
Background: Xtr.NigerianKhok
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR kcnh6 gRNA1 kcnh6
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 45  
Anatomical Phenotypes: abnormal foregut morphology, abnormal gall bladder, abnormal heart looping, abnormal intestine morphology, abnormal left-right axis morphology, increased size of the heart
Human Disease Associations: situs inversus
Source: Fig. 1i
Article: XB-ART-59330, PubMed