Figure 6. FoxA1 drastically enhances AR binding to HRE1/1 + Fox and HRE1/2 + Fox constructs. Groups of oocytes were mRNA injected to express AR or AR together with FoxA1 followed by nuclear injection of HRE1/1 + Fox or HRE1/2 + Fox constructs. (A) AR-HRE binding based on DMS methylation protection plotted as a function of nuclear AR concentration. (B) FoxA1-DNA binding based on DMS methylation protection plotted as a function of nuclear AR concentration.
Image published in: Belikov S et al. (2016)
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