Supplemental Figure S4. (A) The subset of the mesoderm specification network (Koide et al., 2005) as it relates to TFI genes (blue box) and BMP, FGF and Activin/nodal signaling. (B) Hierarchical clustering of TFI genomic interaction network as determined by assigning ChIP‐seq peaks of Lhx1, Gsc, Otx2, Eomes, Vegt and T (Xbra) to genic regions (Methods). In addition, expression changes in gsc and lhx1/otx2/otx5 morphant (Mo) embryos are shown (Yasuoka et al., 2014). Color intensity reflects number of peaks in the locus (ChIP, 0, 1 or >=2 peaks) or Log2 fold expression change (RNA‐seq, yellow decreased, blue increased, grey not determined). The genes shown to the right represent all named X. tropicalis TFI genes.
Image published in: Gazdag E et al. (2016)
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