• 3rd European Amphibian Club

    Ghent, Belgium
    July 1-4, 2022

    Registration now open.

    Click here to go to the meeting site.
    Click here for registration details.

    Early bird registration: April 30.
    Abstract deadline: May 20.
    Registration deadline: June 3.

    Attendance for PhD students is quite affordable.

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  • ARVCF catenin controls force production during vertebrate convergent extension

    Huebner and Weng et al. identify a poorly characterized catenin, Arvcf, as a regulator of force production during vertebrate head-to-tail axis extension. Published in Developmental Cell.

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  • Microridge-like structures anchor motile cilia

    The actin cytoskeleton is highly dynamic during early development of multiciliated cells (MCCs). Yasunaga et al. published in Nature Communications that anchoring subapical actin filaments requires the presence of microridge-like structures formed during MCC development.

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  • Uncovering the mesendoderm gene regulatory network through multi-omic data integration

    Jansen et al. built a pipeline to create GRNs using highly dimensional multi-omic datasets to predict new TF-DNA/TF-TF interactions during mesendoderm development. Published in Cell Reports.

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  • Nutritional control of thyroid morphogenesis through gastrointestinal hormones

    Takagishi et al. publish in Current Biology studying nutritional control of Xenopus thyroid morphology requiring external nutrients. GIP induces thryoid folicle formation.

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  • Xenopus, from basic biology to disease models in the genomic era

    Edited by Abraham Fainsood and Sally A. Moody.

     

    Available for Download, Read Online, or purchase.

     

    Click here to view a PDF flier containing the table of contents. 

     

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  • Development, Growth & Differentiation (DGD) Special Issue

    Call for Papers!

    Submit a manuscript to Development, Growth & Differentiation (Wiley),the official journal of the Japanese Society of Developmental Biologists

    For the special issue “Versatile utilities of amphibians: from molecular, cellular, and developmental biology to physiology”

    Special issue flyer (pdf).

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  • Phenotypes on Xenbase

    The latest release of Xenbase includes the ability to search for Phenotypes.

     

    Click here to go to the Phenotype search page.

     

    Click here to find details on executing a Phenotype search.

     

    Click here to find details on the Xenopus Phenotype Ontology (XPO).

     

     

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  • Xenopus tropicalis v10 genome

    - available to BLAST

    - view on JBrowse

     

    99.86% of the genome mapped to chromosomes
    ~4500 new and refined models, 18% not present in trop v9.1

     

    Click here to view the release document.

    Read More...
  • 3rd European Amphibian Club

    Ghent, Belgium
    July 1-4, 2022

    Registration now open.

    Click here to go to the meeting site.
    Click here for registration details.

    Early bird registration: April 30.
    Abstract deadline: May 20.
    Registration deadline: June 3.

    Attendance for PhD students is quite affordable.

    Read More...

Xenopus is an essential vertebrate model system for biomedical research

  • Share 83% human disease genes
  • Ease of genomic manipulation
  • Large eggs and embryos with rapid external development
  • Ease of housing
  • Produce hardy eggs year-round
  • Learn more about Xenopus


The Xenopus model organism knowledgebase
Xenbase is a web-accessible resource that integrates all the diverse biological, genomic, genotype and phenotype data available from Xenopus research. Learn more about Xenbase.