• 19th International Xenopus Conference

     

    Registration is now open.

    Deadlines: 
    General Registration and Abstract Submission: June 15, 2023.
    Trainee Travel Award application: May 15, 2023.
    Housing: July 30, 2023.

    Visit the conference website.

    Conference poster: please post and share

     

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  • Cold Spring Harbor Laboratory Course

     

    Cell & Developmental Biology of Xenopus: Gene Discovery & Disease

    April 12 - 25, 2023


    Key Dates:

    Application Deadline: January 31, 2023

    Arrival: April 11th by 6pm EST
    Departure: April 25th around 12pm EST

     

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  • Xenopus Bioinformatics Workshop (MBL Course)

     

    April 6-11th, 2023

    Woods Hole, MA, USA

    Registration now open.

     

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  • Cytoplasmic organization promotes protein diffusion in Xenopus extracts

     

    Huang et al. use Xenopus laevis egg extracts as a model system to study diffusion dynamics in organized versus disorganized cytoplasm. Nature Communications.

     

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  • Membrane potential affects pluripotency

     

    Sempou et al. demonstrate the electrical properties of embryonic stem cells can play a critical role in the transition from pluripotency to a differentiated state. Nature Communications.

     

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  • Multiciliated cells probe mechanical environment during epithelial integration

     

    Ventura and Amiri et al. in Nature Communications reveal how migrating cells in the Xenopus embryo join a tissue by using finger-like extensions (filopodia) to read mechanical information from neighboring cells. Adding new cells into tissue is a key process in sculpting organs during normal development, but it is subverted during the metastatic spread of cancer cells.

     

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  • Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex

     

    Zhu et al. published in Science the single-particle cryo–electron microscopy reconstruction of the cytoplasmic ring subunit from the Xenopus laevis nuclear pore complex at 3.7- to 4.7-angstrom resolution.

     

     

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  • Xenbase joins the Alliance of Genome Resources

     

    A big leap forward for Alliance of Genome Resources (AGR) with the inclusion of Xenopus data from Xenbase

     

    Check out the AGR...

     

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  • Normal Table of Xenopus development: a new graphical resource

     

    Zahn et al. published in Develoment a new normal table resource of images chronicling the development of Xenopus frogs.

    View the Zahn drawings and landmarks table on Xenbase.

    View the accompanying poster.

     

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  • Vertebrate Cranial Placodes

     

    Dr. Gerhard Schlosser published a two-volume book set through CRC Press detailing the development and evolution of vertebrate cranial placodes.

     

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  • Phenotypes on Xenbase

    The latest release of Xenbase includes the ability to search for Phenotypes.

     

    Click here to go to the Phenotype search page.

     

    Click here to find details on executing a Phenotype search.

     

    Click here to find details on the Xenopus Phenotype Ontology (XPO).

     

     

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  • Xenopus laevis v10.1 and Xenopus tropicalis v10 genomes

     

    - both genomes fully integrated into Xenbase

    - BLAST mRNA, protein, and CDS

    - viewable on JBrowse

    - morpholino tracks aligned

    - relevant files available on Xenbase FTP and downloads page

     

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  • 19th International Xenopus Conference

     

    Registration is now open.

    Deadlines: 
    General Registration and Abstract Submission: June 15, 2023.
    Trainee Travel Award application: May 15, 2023.
    Housing: July 30, 2023.

    Visit the conference website.

    Conference poster: please post and share

     

    Read More...

Xenopus is an essential vertebrate model system for biomedical research

  • Share 83% human disease genes
  • Ease of genomic manipulation
  • Large eggs and embryos with rapid external development
  • Ease of housing
  • Produce hardy eggs year-round
  • Learn more about Xenopus


The Xenopus model organism knowledgebase
Xenbase is a web-accessible resource that integrates all the diverse biological, genomic, genotype and phenotype data available from Xenopus research. Learn more about Xenbase.