• Normal Table of Xenopus development: a new graphical resource

     

    Zahn et al. published in Develoment a new normal table resource of images chronicling the development of Xenopus frogs.

    View the Zahn drawings and landmarks table on Xenbase.

    View the accompanying poster.

     

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  • Vertebrate Cranial Placodes

     

    Dr. Gerhard Schlosser published a two-volume book set through CRC Press detailing the development and evolution of vertebrate cranial placodes.

     

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  • Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex

     

    Zhu et al. published in Science the single-particle cryo–electron microscopy reconstruction of the cytoplasmic ring subunit from the Xenopus laevis nuclear pore complex at 3.7- to 4.7-angstrom resolution.

     

     

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  • ARVCF catenin controls force production during vertebrate convergent extension

     

    Huebner and Weng et al. identify a poorly characterized catenin, Arvcf, as a regulator of force production during vertebrate head-to-tail axis extension. Published in Developmental Cell.

     

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  • Microridge-like structures anchor motile cilia

     

    The actin cytoskeleton is highly dynamic during early development of multiciliated cells (MCCs). Yasunaga et al. published in Nature Communications that anchoring subapical actin filaments requires the presence of microridge-like structures formed during MCC development.

     

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  • Uncovering the mesendoderm gene regulatory network through multi-omic data integration

     

    Jansen et al. built a pipeline to create GRNs using highly dimensional multi-omic datasets to predict new TF-DNA/TF-TF interactions during mesendoderm development. Published in Cell Reports.

     

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  • Nutritional control of thyroid morphogenesis through gastrointestinal hormones

     

    Takagishi et al. publish in Current Biology studying nutritional control of Xenopus thyroid morphology requiring external nutrients. GIP induces thryoid folicle formation.

     

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  • Xenopus, from basic biology to disease models in the genomic era

    Edited by Abraham Fainsood and Sally A. Moody.

     

    Available for Download, Read Online, or purchase.

     

    Click here to view a PDF flier containing the table of contents. 

     

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  • Phenotypes on Xenbase

    The latest release of Xenbase includes the ability to search for Phenotypes.

     

    Click here to go to the Phenotype search page.

     

    Click here to find details on executing a Phenotype search.

     

    Click here to find details on the Xenopus Phenotype Ontology (XPO).

     

     

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  • Xenopus laevis v10.1 and Xenopus tropicalis v10 genomes

     

    - both genomes fully integrated into Xenbase

    - BLAST mRNA, protein, and CDS

    - viewable on JBrowse

    - morpholino tracks aligned

    - relevant files available on Xenbase FTP and downloads page

     

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  • Normal Table of Xenopus development: a new graphical resource

     

    Zahn et al. published in Develoment a new normal table resource of images chronicling the development of Xenopus frogs.

    View the Zahn drawings and landmarks table on Xenbase.

    View the accompanying poster.

     

    Read More...

Xenopus is an essential vertebrate model system for biomedical research

  • Share 83% human disease genes
  • Ease of genomic manipulation
  • Large eggs and embryos with rapid external development
  • Ease of housing
  • Produce hardy eggs year-round
  • Learn more about Xenopus


The Xenopus model organism knowledgebase
Xenbase is a web-accessible resource that integrates all the diverse biological, genomic, genotype and phenotype data available from Xenopus research. Learn more about Xenbase.