krt12.4 has 38 expression phenotype(s)
Images Sources Experiment + Assay Phenotypes Human Diseases
Fig.4.L-O,V

Tavares ALP et al. (2021)
Xla Wt + sobp

NF16-18 (in situ hybridization)
Expression Phenotype
increased amount krt12.4.L expression in neuroectoderm
decreased amount foxd3.L expression in neural crest
decreased amount six1.L expression in lateral preplacodal ectoderm
increased amount foxd3.L expression in neuroectoderm
Fig.4.B

Tavares ALP et al. (2021)
Xla Wt + sobp

NF16-18 (RT-PCR)
Expression Phenotype
increased amount krt12.4.L expression in the embryo
decreased amount foxd3.L expression in the embryo
decreased amount six1.L expression in the embryo
Fig.4.H-K,U

Tavares ALP et al. (2021)
Xla Wt + sobp CRISPR

NF16-18 (in situ hybridization)
Anatomical Phenotype
increased width of neural plate
Expression Phenotype
decreased amount krt12.4.L expression in epidermis
decreased amount foxd3.L expression in neural crest
decreased amount six1.L expression in lateral preplacodal ectoderm
decreased amount sox2.L expression in neural plate
Fig.4.D-G,T

Tavares ALP et al. (2021)
Xla Wt + sobp MO

NF16-18 (in situ hybridization)
Anatomical Phenotype
increased width of neural plate
Expression Phenotype
decreased amount krt12.4.L expression in epidermis
decreased amount foxd3.L expression in neural crest
decreased amount six1.L expression in lateral preplacodal ectoderm
decreased amount sox2.L expression in neural plate
Fig.4.Q-S,X

Tavares ALP et al. (2021)
Xla Wt + sobpR651X

NF16-18 (in situ hybridization)
Expression Phenotype
increased amount krt12.4.L expression in neuroectoderm
decreased amount foxd3.L expression in neural crest
decreased amount six1.L expression in lateral preplacodal ectoderm
Fig.4.C

Tavares ALP et al. (2021)
Xla Wt + sobpR651X

NF16-18 (RT-PCR)
Expression Phenotype
increased amount krt12.4.L expression in the embryo
decreased amount six1.L expression in the embryo
Fig. 3

Virgirinia RP et al. (2021)
Xla Wt + clk1

NF21 (RT-PCR)
Expression Phenotype
increased amount krt12.4.L expression in Keller explant
decreased amount sox3.L expression in Keller explant
decreased amount zeb2.L expression in Keller explant
increased amount ncam1.L expression in Keller explant
Fig. 3

Virgirinia RP et al. (2021)
Xla Wt + clk2

NF21 (RT-PCR)
Expression Phenotype
decreased amount krt12.4.L expression in Keller explant
increased amount sox3.L expression in Keller explant
increased amount zeb2.L expression in Keller explant
Fig. 3

Virgirinia RP et al. (2021)
Xla Wt + clk3

NF21 (RT-PCR)
Expression Phenotype
decreased amount krt12.4.L expression in Keller explant
increased amount ncam1.L expression in Keller explant
increased amount sox3.L expression in Keller explant
increased amount zeb2.L expression in Keller explant
Fig.6.F

Chen M et al. (2020)
Xla Wt + tmem79 MO

NF16 (in situ hybridization)
Anatomical Phenotype
abnormal neural plate morphology
increased size of the epidermis
Expression Phenotype
increased amount krt12.4.L expression in epidermis
decreased amount sox2.L expression in neural plate
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